HCSGD entry for MSR1

1. General information

Official gene symbolMSR1
Entrez ID4481
Gene full namemacrophage scavenger receptor 1
Other gene symbolsCD204 SCARA1 SR-A SRA phSR1 phSR2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005044Scavenger receptor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005581CollagenIEAcellular_component
GO:0005829CytosolIEAcellular_component
GO:0005886Plasma membraneIEA TAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006898Receptor-mediated endocytosisTASbiological_process
GO:0010744Positive regulation of macrophage derived foam cell differentiationIEA ISSbiological_process
GO:0010886Positive regulation of cholesterol storageIEA ISSbiological_process
GO:0016020MembraneIEAcellular_component
GO:0030169Low-density lipoprotein particle bindingIEA ISSmolecular_function
GO:0030301Cholesterol transportIEA ISSbiological_process
GO:0030666Endocytic vesicle membraneTAScellular_component
GO:0031410Cytoplasmic vesicleIEAcellular_component
GO:0034362Low-density lipoprotein particleIEAcellular_component
GO:0034381Plasma lipoprotein particle clearanceIEA ISSbiological_process
GO:0042953Lipoprotein transportIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.81230076360.37193033320.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0975997196
GSE13712_SHEARDown-0.0231731853
GSE13712_STATICUp0.0179079380
GSE19018Up0.0816373763
GSE19899_A1Up0.0648482308
GSE19899_A2Down-0.0245012787
PubMed_21979375_A1Down-0.1759433526
PubMed_21979375_A2Down-0.0156314299
GSE35957Up0.3647159540
GSE36640Up0.0144389538
GSE54402Down-0.2180913394
GSE9593Down-0.0137851701
GSE43922Up0.0191538524
GSE24585Down-0.1552727942
GSE37065Up0.0324627059
GSE28863_A1Down-0.6929634757
GSE28863_A2Up0.2726010569
GSE28863_A3Up0.0510664225
GSE28863_A4Down-0.0374054961
GSE48662Up0.2043216430

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.