HCSGD entry for MSH5


1. General information

Official gene symbolMSH5
Entrez ID4439
Gene full namemutS homolog 5 (E. coli)
Other gene symbolsG7 MUTSH5 NG23
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000710Meiotic mismatch repairIRDbiological_process
GO:0000795Synaptonemal complexIBAcellular_component
GO:0003677DNA bindingIEAmolecular_function
GO:0003684Damaged DNA bindingIRDmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0006200ATP catabolic processIBAbiological_process
GO:0006298Mismatch repairIEA TASbiological_process
GO:0007126MeiosisTASbiological_process
GO:0007131Reciprocal meiotic recombinationIBAbiological_process
GO:0007136Meiotic prophase IITASbiological_process
GO:0008094DNA-dependent ATPase activityIBAmolecular_function
GO:0016887ATPase activityIEAmolecular_function
GO:0030983Mismatched DNA bindingIBA IEAmolecular_function
GO:0032300Mismatch repair complexIRDcellular_component
GO:0045143Homologous chromosome segregationIBAbiological_process
GO:0045910Negative regulation of DNA recombinationIEAbiological_process
GO:0051026Chiasma assemblyIBAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.95491024660.46616322330.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954--
GSE13712_SHEAR--
GSE13712_STATIC--
GSE19018--
GSE19899_A1--
GSE19899_A2--
PubMed_21979375_A1--
PubMed_21979375_A2--
GSE35957--
GSE36640--
GSE54402--
GSE9593--
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Down-0.0117276274
GSE28863_A2Up0.6481282490
GSE28863_A3Down-0.2291433988
GSE28863_A4Down-0.0425233302
GSE48662Down-0.4061848522

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.