HCSGD entry for ASMT

1. General information

Official gene symbolASMT
Entrez ID438
Gene full nameacetylserotonin O-methyltransferase
Other gene symbolsASMTY HIOMT HIOMTY
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005829CytosolTAScellular_component
GO:0006412TranslationTASbiological_process
GO:0008171O-methyltransferase activityIEA TASmolecular_function
GO:0017096Acetylserotonin O-methyltransferase activityIDAmolecular_function
GO:0030187Melatonin biosynthetic processIDA IEAbiological_process
GO:0034641Cellular nitrogen compound metabolic processTASbiological_process
GO:0042802Identical protein bindingIPImolecular_function
GO:0042803Protein homodimerization activityIPImolecular_function
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046219Indolalkylamine biosynthetic processTASbiological_process
GO:2000019Negative regulation of male gonad developmentIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.64615451920.93147369400.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0186834291
GSE13712_SHEARDown-0.0816226618
GSE13712_STATICUp0.0568575851
GSE19018Up0.0985256047
GSE19899_A1Up0.1752695123
GSE19899_A2Up0.0827710297
PubMed_21979375_A1Up0.1145871781
PubMed_21979375_A2Down-0.0776583285
GSE35957Up0.0944155736
GSE36640Up0.0634470787
GSE54402Up0.0560106634
GSE9593Down-0.0202545864
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.0985726606

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

MelatoninDB01065 APRD00742 | DB08189

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.