HCSGD entry for ABCC1
1. General information
| Official gene symbol | ABCC1 |
|---|---|
| Entrez ID | 4363 |
| Gene full name | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 |
| Other gene symbols | ABC29 ABCC GS-X MRP MRP1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005215 | Transporter activity | TAS | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | IEA | cellular_component |
| GO:0006200 | ATP catabolic process | IDA TAS | biological_process |
| GO:0006691 | Leukotriene metabolic process | TAS | biological_process |
| GO:0006766 | Vitamin metabolic process | TAS | biological_process |
| GO:0006767 | Water-soluble vitamin metabolic process | TAS | biological_process |
| GO:0006810 | Transport | TAS | biological_process |
| GO:0009235 | Cobalamin metabolic process | TAS | biological_process |
| GO:0016020 | Membrane | TAS | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016887 | ATPase activity | IDA | molecular_function |
| GO:0019369 | Arachidonic acid metabolic process | TAS | biological_process |
| GO:0042493 | Response to drug | TAS | biological_process |
| GO:0042626 | ATPase activity, coupled to transmembrane movement of substances | IEA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4822853919 | 0.0206218153 | 0.9999902473 | 0.2777823951 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2005289311 |
| GSE13712_SHEAR | Down | -0.4165425153 |
| GSE13712_STATIC | Down | -0.0725401539 |
| GSE19018 | Down | -0.7409337999 |
| GSE19899_A1 | Down | -0.5505924701 |
| GSE19899_A2 | Down | -1.0579235526 |
| PubMed_21979375_A1 | Down | -0.9932374257 |
| PubMed_21979375_A2 | Down | -0.0076819124 |
| GSE35957 | Up | 0.0196573226 |
| GSE36640 | Up | 0.0453876403 |
| GSE54402 | Down | -0.3458355491 |
| GSE9593 | Up | 0.1636809933 |
| GSE43922 | Down | -0.6245873479 |
| GSE24585 | Down | -0.6128699187 |
| GSE37065 | Up | 0.3733886741 |
| GSE28863_A1 | Up | 1.2973758063 |
| GSE28863_A2 | Up | 0.9624060986 |
| GSE28863_A3 | Down | -0.0303092799 |
| GSE28863_A4 | Up | 0.0107252692 |
| GSE48662 | Up | 0.0564215307 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-7-5p | MIMAT0000252 | MIRT003199 | Luciferase reporter assay//Western blot | Functional MTI | 20099276 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT003199 | Microarray | Functional MTI (Weak) | 19073608 |
| hsa-miR-345-5p | MIMAT0000772 | MIRT003198 | Luciferase reporter assay//Western blot | Functional MTI | 20099276 |
| hsa-miR-134-5p | MIMAT0000447 | MIRT004494 | qRT-PCR//Western blot//Northern blot | Functional MTI | 20371173 |
| hsa-miR-9-5p | MIMAT0000441 | MIRT021440 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-1 | MIMAT0000416 | MIRT024051 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027818 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032483 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040354 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-339-5p | MIMAT0000764 | MIRT042744 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT046005 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-23b-3p | MIMAT0000418 | MIRT046316 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT051224 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
