HCSGD entry for MPP2
1. General information
| Official gene symbol | MPP2 |
|---|---|
| Entrez ID | 4355 |
| Gene full name | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) |
| Other gene symbols | DLG2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004385 | Guanylate kinase activity | TAS | molecular_function |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0008152 | Metabolic process | TAS | biological_process |
| GO:0016020 | Membrane | TAS | cellular_component |
| GO:0016310 | Phosphorylation | TAS | biological_process |
| GO:0030165 | PDZ domain binding | IEA | molecular_function |
| GO:0046939 | Nucleotide phosphorylation | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6290643897 | 0.1949283044 | 0.9999902473 | 0.8553733167 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3164311076 |
| GSE13712_SHEAR | Down | -0.0234969488 |
| GSE13712_STATIC | Up | 0.0317161666 |
| GSE19018 | Up | 0.3240162628 |
| GSE19899_A1 | Down | -0.0589034931 |
| GSE19899_A2 | Down | -0.0864806622 |
| PubMed_21979375_A1 | Down | -0.0914247585 |
| PubMed_21979375_A2 | Down | -0.0395935183 |
| GSE35957 | Down | -0.3804713646 |
| GSE36640 | Up | 0.6390059633 |
| GSE54402 | Up | 0.1195657961 |
| GSE9593 | Up | 0.1408770842 |
| GSE43922 | Down | -0.0251048001 |
| GSE24585 | Up | 0.0997664708 |
| GSE37065 | Down | -0.0360345048 |
| GSE28863_A1 | Up | 0.1879539554 |
| GSE28863_A2 | Down | -0.7674815710 |
| GSE28863_A3 | Down | -0.0522516656 |
| GSE28863_A4 | Down | -0.2940694615 |
| GSE48662 | Up | 0.2471524978 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020593 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-128-3p | MIMAT0000424 | MIRT021960 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028414 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1229-3p | MIMAT0005584 | MIRT036323 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-296-3p | MIMAT0004679 | MIRT038475 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040407 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT042248 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-196a-5p | MIMAT0000226 | MIRT048275 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
