HCSGD entry for MNT
1. General information
| Official gene symbol | MNT |
|---|---|
| Entrez ID | 4335 |
| Gene full name | MNT, MAX dimerization protein |
| Other gene symbols | MAD6 MXD6 ROX bHLHd3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003682 | Chromatin binding | IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0003713 | Transcription coactivator activity | TAS | molecular_function |
| GO:0003714 | Transcription corepressor activity | TAS | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0007275 | Multicellular organismal development | TAS | biological_process |
| GO:0007569 | Cell aging | IEA | biological_process |
| GO:0008285 | Negative regulation of cell proliferation | TAS | biological_process |
| GO:0046983 | Protein dimerization activity | IEA | molecular_function |
| GO:0051726 | Regulation of cell cycle | IEA | biological_process |
| GO:2001234 | Negative regulation of apoptotic signaling pathway | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1241980130 | 0.9371250104 | 0.7196853401 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2388388370 |
| GSE13712_SHEAR | Up | 0.0323559574 |
| GSE13712_STATIC | Up | 0.1146068031 |
| GSE19018 | Up | 0.5860610774 |
| GSE19899_A1 | Down | -0.2054306262 |
| GSE19899_A2 | Up | 0.1705421728 |
| PubMed_21979375_A1 | Up | 0.1555908152 |
| PubMed_21979375_A2 | Up | 0.5079924675 |
| GSE35957 | Up | 0.2455813754 |
| GSE36640 | Up | 0.0960767880 |
| GSE54402 | Up | 0.1131983854 |
| GSE9593 | Up | 0.1684206326 |
| GSE43922 | Up | 0.1114107666 |
| GSE24585 | Down | -0.1619941091 |
| GSE37065 | Down | -0.0274272194 |
| GSE28863_A1 | Up | 0.1339464111 |
| GSE28863_A2 | Up | 0.0745216532 |
| GSE28863_A3 | Up | 0.3232759644 |
| GSE28863_A4 | Up | 0.1494838159 |
| GSE48662 | Up | 0.2367680265 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-210-3p | MIMAT0000267 | MIRT004672 | Luciferase reporter assay//qRT-PCR//Western blot | Functional MTI | 19652553 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043556 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT050948 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
