HCSGD entry for ALDH6A1
1. General information
| Official gene symbol | ALDH6A1 |
|---|---|
| Entrez ID | 4329 |
| Gene full name | aldehyde dehydrogenase 6 family, member A1 |
| Other gene symbols | MMSADHA MMSDH |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000062 | Fatty-acyl-CoA binding | ISS | molecular_function |
| GO:0004491 | Methylmalonate-semialdehyde dehydrogenase (acylating) activity | IEA ISS | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IDA NAS | cellular_component |
| GO:0005759 | Mitochondrial matrix | TAS | cellular_component |
| GO:0006573 | Valine metabolic process | ISS | biological_process |
| GO:0009083 | Branched-chain amino acid catabolic process | TAS | biological_process |
| GO:0018478 | Malonate-semialdehyde dehydrogenase (acetylating) activity | ISS | molecular_function |
| GO:0019859 | Thymine metabolic process | ISS | biological_process |
| GO:0034641 | Cellular nitrogen compound metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0050873 | Brown fat cell differentiation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9813108089 | 0.0016610577 | 0.9999902473 | 0.0784334526 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1380075206 |
| GSE13712_SHEAR | Down | -1.1465709675 |
| GSE13712_STATIC | Down | -1.0801854738 |
| GSE19018 | Up | 0.2712396887 |
| GSE19899_A1 | Down | -1.2750280653 |
| GSE19899_A2 | Down | -1.1939586990 |
| PubMed_21979375_A1 | Down | -1.3263028898 |
| PubMed_21979375_A2 | Down | -1.6323449562 |
| GSE35957 | Down | -0.3759680693 |
| GSE36640 | Down | -0.3252037569 |
| GSE54402 | Down | -0.9658736436 |
| GSE9593 | Down | -0.3333629975 |
| GSE43922 | Down | -0.9120864147 |
| GSE24585 | Up | 0.6843951166 |
| GSE37065 | Down | -0.3179734684 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.2578817739 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| NADH | DB00157 | NUTR00041 | DB01907 | EXPT02287 | DB03527 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-320e | MIMAT0015072 | MIRT052812 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
