HCSGD entry for MKI67
1. General information
| Official gene symbol | MKI67 |
|---|---|
| Entrez ID | 4288 |
| Gene full name | antigen identified by monoclonal antibody Ki-67 |
| Other gene symbols | KIA |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000775 | Chromosome, centromeric region | IEA | cellular_component |
| GO:0000793 | Condensed chromosome | IEA | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006259 | DNA metabolic process | IEA | biological_process |
| GO:0007126 | Meiosis | IEA | biological_process |
| GO:0008022 | Protein C-terminus binding | IPI | molecular_function |
| GO:0008283 | Cell proliferation | TAS | biological_process |
| GO:0014070 | Response to organic cyclic compound | IEA | biological_process |
| GO:0030212 | Hyaluronan metabolic process | IEA | biological_process |
| GO:0031100 | Organ regeneration | IEA | biological_process |
| GO:0034605 | Cellular response to heat | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4504176513 | 0.0000209908 | 0.9999902473 | 0.0084212121 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.5540543529 |
| GSE13712_SHEAR | Down | -0.3793984609 |
| GSE13712_STATIC | Down | -0.7401214738 |
| GSE19018 | Up | 0.1514567001 |
| GSE19899_A1 | Down | -0.6710825058 |
| GSE19899_A2 | Down | -4.0314067526 |
| PubMed_21979375_A1 | Down | -3.6667188855 |
| PubMed_21979375_A2 | Down | -3.1196568145 |
| GSE35957 | Down | -3.0544249210 |
| GSE36640 | Down | -5.3786716203 |
| GSE54402 | Down | -1.2968760514 |
| GSE9593 | Down | -1.1014806159 |
| GSE43922 | Down | -3.5206173551 |
| GSE24585 | Down | -0.2726568508 |
| GSE37065 | Down | -1.3173722715 |
| GSE28863_A1 | Up | 0.4447607192 |
| GSE28863_A2 | Up | 1.8745750373 |
| GSE28863_A3 | Up | 0.0592113630 |
| GSE28863_A4 | Up | 0.5387409694 |
| GSE48662 | Down | -1.1176675578 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023674 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024267 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025361 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026336 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031529 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1909-5p | MIMAT0007882 | MIRT035804 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-1296-5p | MIMAT0005794 | MIRT036119 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT037098 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040461 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-505-3p | MIMAT0002876 | MIRT041044 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041876 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043477 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-328-3p | MIMAT0000752 | MIRT043812 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-221-3p | MIMAT0000278 | MIRT046919 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-29b-3p | MIMAT0000100 | MIRT048383 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049015 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT051037 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051657 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
