HCSGD entry for MIP

1. General information

Official gene symbolMIP
Entrez ID4284
Gene full namemajor intrinsic protein of lens fiber
Other gene symbolsAQP0 LIM1 MIP26 MP26
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002088Lens development in camera-type eyeIEAbiological_process
GO:0005212Structural constituent of eye lensIEAmolecular_function
GO:0005215Transporter activityTASmolecular_function
GO:0005516Calmodulin bindingISSmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneISScellular_component
GO:0005921Gap junctionIEAcellular_component
GO:0006833Water transportISS TASbiological_process
GO:0007601Visual perceptionIEAbiological_process
GO:0015250Water channel activityISSmolecular_function
GO:0015722Canalicular bile acid transportIEAbiological_process
GO:0043231Intracellular membrane-bounded organelleIEAcellular_component
GO:0046691Intracellular canaliculusIEAcellular_component
GO:0050896Response to stimulusIEAbiological_process
GO:0055085Transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.42851928880.91988899360.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0430524945
GSE13712_SHEARUp0.0685541525
GSE13712_STATICUp0.2077935089
GSE19018Up0.2376187832
GSE19899_A1Up0.0321770682
GSE19899_A2Up0.0211189756
PubMed_21979375_A1Up0.3254420672
PubMed_21979375_A2Up0.0223412083
GSE35957Up0.0916370189
GSE36640Down-0.1604900434
GSE54402Down-0.0398422463
GSE9593Up0.0605462890
GSE43922Up0.0159754187
GSE24585Up0.3081779081
GSE37065Up0.0932484155
GSE28863_A1Down-0.0846222896
GSE28863_A2Down-0.1451760661
GSE28863_A3Up0.0929555720
GSE28863_A4Up0.0499428944
GSE48662Up0.1777298391

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.