HCSGD entry for MGST3


1. General information

Official gene symbolMGST3
Entrez ID4259
Gene full namemicrosomal glutathione S-transferase 3
Other gene symbolsGST-III
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004364Glutathione transferase activityIBAmolecular_function
GO:0004601Peroxidase activityTASmolecular_function
GO:0004602Glutathione peroxidase activityIBAmolecular_function
GO:0005635Nuclear envelopeIBAcellular_component
GO:0005789Endoplasmic reticulum membraneTAScellular_component
GO:0006629Lipid metabolic processTASbiological_process
GO:0006805Xenobiotic metabolic processTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0016020MembraneTAScellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0043231Intracellular membrane-bounded organelleTAScellular_component
GO:0044281Small molecule metabolic processTASbiological_process
GO:0055114Oxidation-reduction processIBA TASbiological_process
GO:1901687Glutathione derivative biosynthetic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.65418376200.26243917780.99999024730.9837344346

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0086081833
GSE13712_SHEARUp0.0541580524
GSE13712_STATICDown-0.0474801588
GSE19018Up0.4873495974
GSE19899_A1Down-0.1744591948
GSE19899_A2Down-0.2261164963
PubMed_21979375_A1Down-0.5634385707
PubMed_21979375_A2Down-0.1600604328
GSE35957Up0.2813738015
GSE36640Down-0.0326225134
GSE54402Down-0.0894164663
GSE9593Up0.1042580908
GSE43922Down-0.2466800852
GSE24585Up0.2078484787
GSE37065Up0.1074275503
GSE28863_A1Up0.1405285490
GSE28863_A2Up0.3902574704
GSE28863_A3Down-0.3661042143
GSE28863_A4Down-0.3419856468
GSE48662Down-0.0288502249

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

GlutathioneDB00143 NUTR00029 | EXPT01650

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029259MicroarrayFunctional MTI (Weak)19088304
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.