HCSGD entry for MGST2
1. General information
| Official gene symbol | MGST2 |
|---|---|
| Entrez ID | 4258 |
| Gene full name | microsomal glutathione S-transferase 2 |
| Other gene symbols | GST2 MGST-II |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004364 | Glutathione transferase activity | IDA | molecular_function |
| GO:0004464 | Leukotriene-C4 synthase activity | IDA | molecular_function |
| GO:0004602 | Glutathione peroxidase activity | IBA | molecular_function |
| GO:0005635 | Nuclear envelope | IBA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006750 | Glutathione biosynthetic process | IDA | biological_process |
| GO:0006805 | Xenobiotic metabolic process | TAS | biological_process |
| GO:0008047 | Enzyme activator activity | IEA | molecular_function |
| GO:0010243 | Response to organonitrogen compound | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0019370 | Leukotriene biosynthetic process | IDA | biological_process |
| GO:0032496 | Response to lipopolysaccharide | IEA | biological_process |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0055114 | Oxidation-reduction process | IBA | biological_process |
| GO:1901687 | Glutathione derivative biosynthetic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0346296607 | 0.5779072338 | 0.4261199164 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4261277683 |
| GSE13712_SHEAR | Down | -0.0689188278 |
| GSE13712_STATIC | Down | -0.0812012922 |
| GSE19018 | Up | 0.2837872024 |
| GSE19899_A1 | Down | -0.1880325686 |
| GSE19899_A2 | Up | 0.2464611809 |
| PubMed_21979375_A1 | Down | -0.1272625518 |
| PubMed_21979375_A2 | Up | 1.5432887422 |
| GSE35957 | Up | 0.8700437015 |
| GSE36640 | Up | 0.6313879754 |
| GSE54402 | Down | -0.8513144057 |
| GSE9593 | Up | 0.5868413718 |
| GSE43922 | Up | 0.3198994960 |
| GSE24585 | Up | 0.0176337392 |
| GSE37065 | Up | 0.2392272679 |
| GSE28863_A1 | Down | -0.1389494806 |
| GSE28863_A2 | Down | -0.1450716620 |
| GSE28863_A3 | Down | -0.1989241080 |
| GSE28863_A4 | Down | -0.0673873443 |
| GSE48662 | Up | 0.3988496642 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Glutathione | DB00143 | NUTR00029 | EXPT01650 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020512 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028440 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-340-3p | MIMAT0000750 | MIRT043852 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
