HCSGD entry for METTL1
1. General information
| Official gene symbol | METTL1 |
|---|---|
| Entrez ID | 4234 |
| Gene full name | methyltransferase like 1 |
| Other gene symbols | C12orf1 TRM8 TRMT8 YDL201w |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000049 | TRNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006400 | TRNA modification | IDA | biological_process |
| GO:0008176 | TRNA (guanine-N7-)-methyltransferase activity | IDA IEA | molecular_function |
| GO:0036265 | RNA (guanine-N7)-methylation | IDA | biological_process |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7104431367 | 0.0764769044 | 0.9999902473 | 0.5224366987 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0417411194 |
| GSE13712_SHEAR | Up | 0.4608974441 |
| GSE13712_STATIC | Up | 0.1625105369 |
| GSE19018 | Down | -0.5660962888 |
| GSE19899_A1 | Down | -0.1512134474 |
| GSE19899_A2 | Down | -0.0958839256 |
| PubMed_21979375_A1 | Up | 0.8196329425 |
| PubMed_21979375_A2 | Down | -0.5458040081 |
| GSE35957 | Down | -0.0922051949 |
| GSE36640 | Down | -0.6337987062 |
| GSE54402 | Up | 0.1966636945 |
| GSE9593 | Down | -0.2623162825 |
| GSE43922 | Down | -0.0325728989 |
| GSE24585 | Down | -0.5127990828 |
| GSE37065 | Down | -0.0030189645 |
| GSE28863_A1 | Down | -0.0873884687 |
| GSE28863_A2 | Down | -0.1429617828 |
| GSE28863_A3 | Up | 0.0663367887 |
| GSE28863_A4 | Up | 0.0380573458 |
| GSE48662 | Down | -0.2442692595 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
