HCSGD entry for MEP1A
1. General information
| Official gene symbol | MEP1A |
|---|---|
| Entrez ID | 4224 |
| Gene full name | meprin A, alpha (PABA peptide hydrolase) |
| Other gene symbols | PPHA |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004222 | Metalloendopeptidase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005615 | Extracellular space | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0007586 | Digestion | TAS | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0017090 | Meprin A complex | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5457046503 | 0.7945271646 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0470602628 |
| GSE13712_SHEAR | Up | 0.1232506043 |
| GSE13712_STATIC | Up | 0.1466752042 |
| GSE19018 | Up | 0.0670603173 |
| GSE19899_A1 | Down | -0.0598119103 |
| GSE19899_A2 | Up | 0.0263828814 |
| PubMed_21979375_A1 | Down | -0.3085945061 |
| PubMed_21979375_A2 | Up | 0.1282134266 |
| GSE35957 | Down | -0.0397573422 |
| GSE36640 | Up | 0.0755361764 |
| GSE54402 | Up | 0.1760434596 |
| GSE9593 | Down | -0.1549329462 |
| GSE43922 | Up | 0.0138019784 |
| GSE24585 | Up | 0.1175200761 |
| GSE37065 | Down | -0.0228281285 |
| GSE28863_A1 | Down | -0.0727947103 |
| GSE28863_A2 | Up | 0.0873453021 |
| GSE28863_A3 | Up | 0.1368947342 |
| GSE28863_A4 | Up | 0.2134926024 |
| GSE48662 | Up | 0.0126556257 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT028824 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
