HCSGD entry for RAB8A

1. General information

Official gene symbolRAB8A
Entrez ID4218
Gene full nameRAB8A, member RAS oncogene family
Other gene symbolsMEL RAB8
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000086G2/M transition of mitotic cell cycleTASbiological_process
GO:0000139Golgi membraneTAScellular_component
GO:0000278Mitotic cell cycleTASbiological_process
GO:0003924GTPase activityEXPmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005525GTP bindingIDA IEAmolecular_function
GO:0005886Plasma membraneIEAcellular_component
GO:0005929CiliumIDAcellular_component
GO:0006184GTP catabolic processEXPbiological_process
GO:0006904Vesicle docking involved in exocytosisIDAbiological_process
GO:0007264Small GTPase mediated signal transductionIEAbiological_process
GO:0007409AxonogenesisISSbiological_process
GO:0008152Metabolic processEXPbiological_process
GO:0014069Postsynaptic densityIEAcellular_component
GO:0015031Protein transportIEAbiological_process
GO:0017137Rab GTPase bindingISSmolecular_function
GO:0019003GDP bindingIDAmolecular_function
GO:0019901Protein kinase bindingIEAmolecular_function
GO:0030425DendriteIEAcellular_component
GO:0030659Cytoplasmic vesicle membraneTAScellular_component
GO:0030670Phagocytic vesicle membraneIEAcellular_component
GO:0031513Nonmotile primary ciliumIDAcellular_component
GO:0032869Cellular response to insulin stimulusISSbiological_process
GO:0042384Cilium assemblyIDA IMPbiological_process
GO:0043025Neuronal cell bodyIEAcellular_component
GO:0045335Phagocytic vesicleIDAcellular_component
GO:0048169Regulation of long-term neuronal synaptic plasticityIEAbiological_process
GO:0048210Golgi vesicle fusion to target membraneIDAbiological_process
GO:0051223Regulation of protein transportIEAbiological_process
GO:0055038Recycling endosome membraneIDAcellular_component
GO:0072659Protein localization to plasma membraneISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.82050557350.10039659210.99999024730.6074801609

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1805784266
GSE13712_SHEARUp0.3165407864
GSE13712_STATICUp0.0788003330
GSE19018Up0.1097649508
GSE19899_A1Down-0.1290623748
GSE19899_A2Up0.1329916144
PubMed_21979375_A1Up0.4580805187
PubMed_21979375_A2Down-0.0195954756
GSE35957Down-0.0957788551
GSE36640Down-0.5946031033
GSE54402Up0.1235641314
GSE9593Down-0.0075802421
GSE43922Down-0.0343140371
GSE24585Down-0.3414863344
GSE37065Up0.0542467289
GSE28863_A1Down-0.6545651395
GSE28863_A2Down-0.5340750720
GSE28863_A3Down-0.3146695348
GSE28863_A4Up0.0367141110
GSE48662Down-0.1095344108

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT023153MicroarrayFunctional MTI (Weak)18668037
hsa-miR-26b-5pMIMAT0000083MIRT030290MicroarrayFunctional MTI (Weak)19088304
hsa-miR-92a-3pMIMAT0000092MIRT049530CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.