HCSGD entry for MEIS2
1. General information
| Official gene symbol | MEIS2 |
|---|---|
| Entrez ID | 4212 |
| Gene full name | Meis homeobox 2 |
| Other gene symbols | HsT18361 MRG1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0001654 | Eye development | IEA | biological_process |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0003712 | Transcription cofactor activity | IEA ISS | molecular_function |
| GO:0003714 | Transcription corepressor activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0008134 | Transcription factor binding | IEA ISS | molecular_function |
| GO:0009612 | Response to mechanical stimulus | IEA | biological_process |
| GO:0031016 | Pancreas development | IEA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IDA IEA | molecular_function |
| GO:0045638 | Negative regulation of myeloid cell differentiation | IEA ISS | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0070848 | Response to growth factor | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9597373314 | 0.0001841761 | 0.9999902473 | 0.0245860000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.7118145022 |
| GSE13712_SHEAR | Down | -0.2640085655 |
| GSE13712_STATIC | Down | -0.2869253717 |
| GSE19018 | Down | -0.4134725025 |
| GSE19899_A1 | Down | -1.4598319257 |
| GSE19899_A2 | Down | -1.9954019791 |
| PubMed_21979375_A1 | Down | -2.2887172675 |
| PubMed_21979375_A2 | Down | -2.2462116953 |
| GSE35957 | Down | -0.2893917910 |
| GSE36640 | Down | -2.6380866659 |
| GSE54402 | Down | -0.6307580121 |
| GSE9593 | Down | -0.5422399045 |
| GSE43922 | Down | -1.6277430815 |
| GSE24585 | Up | 0.2676897171 |
| GSE37065 | Up | 0.1550644438 |
| GSE28863_A1 | Up | 0.7267235758 |
| GSE28863_A2 | Down | -1.3013113671 |
| GSE28863_A3 | Down | -0.7853353372 |
| GSE28863_A4 | Up | 0.3408361974 |
| GSE48662 | Down | -0.3844664296 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-204-5p | MIMAT0000265 | MIRT003546 | Luciferase reporter assay//Western blot | Functional MTI | 20713703 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024859 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026864 | Microarray | Functional MTI (Weak) | 19074876 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
