HCSGD entry for MCF2


1. General information

Official gene symbolMCF2
Entrez ID4168
Gene full nameMCF.2 cell line derived transforming sequence
Other gene symbolsARHGEF21 DBL
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005089Rho guanyl-nucleotide exchange factor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005829CytosolTAScellular_component
GO:0005856CytoskeletonTAScellular_component
GO:0007264Small GTPase mediated signal transductionTASbiological_process
GO:0016020MembraneIEAcellular_component
GO:0016358Dendrite developmentIEAbiological_process
GO:0035556Intracellular signal transductionIEAbiological_process
GO:0043065Positive regulation of apoptotic processTASbiological_process
GO:0048011Neurotrophin TRK receptor signaling pathwayTASbiological_process
GO:0051056Regulation of small GTPase mediated signal transductionTASbiological_process
GO:0097190Apoptotic signaling pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.45829683900.94098778540.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0546860683
GSE13712_SHEARDown-0.0009188648
GSE13712_STATICDown-0.1123603869
GSE19018Up0.2151682276
GSE19899_A1Up0.1217207714
GSE19899_A2Up0.0370062806
PubMed_21979375_A1Up0.0536619307
PubMed_21979375_A2Up0.0069277493
GSE35957Up0.0350750887
GSE36640Up0.1633838331
GSE54402Up0.1067580890
GSE9593Down-0.0347352083
GSE43922Up0.0194052339
GSE24585Up0.2780233575
GSE37065Down-0.0048329964
GSE28863_A1Up0.0710210122
GSE28863_A2Down-0.0098318680
GSE28863_A3Up0.3061509628
GSE28863_A4Down-0.0007896669
GSE48662Down-0.1055159425

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.