HCSGD entry for MCC
1. General information
| Official gene symbol | MCC |
|---|---|
| Entrez ID | 4163 |
| Gene full name | mutated in colorectal cancers |
| Other gene symbols | MCC1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004872 | Receptor activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0010633 | Negative regulation of epithelial cell migration | IMP | biological_process |
| GO:0016055 | Wnt signaling pathway | IEA | biological_process |
| GO:0030027 | Lamellipodium | IEA | cellular_component |
| GO:0050680 | Negative regulation of epithelial cell proliferation | IDA | biological_process |
| GO:0090090 | Negative regulation of canonical Wnt signaling pathway | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0846508225 | 0.2518356901 | 0.6116097447 | 0.9637346903 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3386378882 |
| GSE13712_SHEAR | Up | 0.4737327635 |
| GSE13712_STATIC | Up | 0.2295992618 |
| GSE19018 | Down | -1.0273164948 |
| GSE19899_A1 | Down | -0.2049287908 |
| GSE19899_A2 | Down | -0.0069569232 |
| PubMed_21979375_A1 | Up | 0.1500868492 |
| PubMed_21979375_A2 | Up | 1.1561916692 |
| GSE35957 | Up | 0.0828705350 |
| GSE36640 | Up | 0.1494931323 |
| GSE54402 | Down | -1.0905784638 |
| GSE9593 | Down | -0.0275940177 |
| GSE43922 | Up | 0.5071665671 |
| GSE24585 | Down | -0.1075960303 |
| GSE37065 | Up | 0.0980718424 |
| GSE28863_A1 | Up | 0.2526690284 |
| GSE28863_A2 | Up | 0.1832919528 |
| GSE28863_A3 | Up | 0.0423088884 |
| GSE28863_A4 | Down | -0.0241279189 |
| GSE48662 | Up | 0.0178263409 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-9-5p | MIMAT0000441 | MIRT021365 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029556 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
