HCSGD entry for MC5R


1. General information

Official gene symbolMC5R
Entrez ID4161
Gene full namemelanocortin 5 receptor
Other gene symbolsMC2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004977Melanocortin receptor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneIEA TAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0007187G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messengerTASbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0030819Positive regulation of cAMP biosynthetic processIDAbiological_process
GO:0042562Hormone bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.33033058390.73048988260.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1087856387
GSE13712_SHEARUp0.0922919360
GSE13712_STATICUp0.2244413015
GSE19018Up0.2227548698
GSE19899_A1Up0.3630126279
GSE19899_A2Up0.0467172712
PubMed_21979375_A1Up0.2714377823
PubMed_21979375_A2Down-0.1241883137
GSE35957Up0.2510000274
GSE36640Down-0.0522741747
GSE54402Down-0.0588171082
GSE9593Down-0.1314235196
GSE43922Up0.0144841640
GSE24585Up0.2554985277
GSE37065Up0.0541638306
GSE28863_A1Down-0.1006623355
GSE28863_A2Down-0.2581034697
GSE28863_A3Up0.2612511373
GSE28863_A4Up0.0833219752
GSE48662Down-0.3519705704

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.