HCSGD entry for MC3R

1. General information

Official gene symbolMC3R
Entrez ID4159
Gene full namemelanocortin 3 receptor
Other gene symbolsBMIQ9 MC3 MC3-R OB20 OQTL
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002027Regulation of heart rateIEAbiological_process
GO:0004977Melanocortin receptor activityTASmolecular_function
GO:0004980Melanocyte-stimulating hormone receptor activityIPImolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0007187G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messengerTASbiological_process
GO:0007188Adenylate cyclase-modulating G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0007200Phospholipase C-activating G-protein coupled receptor signaling pathwayTASbiological_process
GO:0008217Regulation of blood pressureIEAbiological_process
GO:0017046Peptide hormone bindingIEAmolecular_function
GO:0030819Positive regulation of cAMP biosynthetic processIDAbiological_process
GO:0042309HomoiothermyIEAbiological_process
GO:0042923Neuropeptide bindingIPImolecular_function
GO:0055078Sodium ion homeostasisIEAbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.82431364310.64848329470.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0021123135
GSE13712_SHEARUp0.0001812716
GSE13712_STATICUp0.1837235439
GSE19018Up0.0894863094
GSE19899_A1Down-0.0171597146
GSE19899_A2Up0.1688218179
PubMed_21979375_A1Up0.0207797897
PubMed_21979375_A2Down-0.2623112190
GSE35957Up0.0529008824
GSE36640Down-0.0163679480
GSE54402Down-0.1012328220
GSE9593Down-0.1175441573
GSE43922Up0.0212561550
GSE24585Up0.0736629121
GSE37065Up0.0633982174
GSE28863_A1Down-0.0087285171
GSE28863_A2Up0.0056815364
GSE28863_A3Up0.0775262094
GSE28863_A4Up0.0222788448
GSE48662Down-0.2936815871

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.