HCSGD entry for MC2R

1. General information

Official gene symbolMC2R
Entrez ID4158
Gene full namemelanocortin 2 receptor (adrenocorticotropic hormone)
Other gene symbolsACTHR
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001890Placenta developmentIEAbiological_process
GO:0004977Melanocortin receptor activityTASmolecular_function
GO:0004978Corticotropin receptor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005886Plasma membraneIEA TAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0007186G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007187G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messengerTASbiological_process
GO:0007218Neuropeptide signaling pathwayTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0030819Positive regulation of cAMP biosynthetic processIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.26566725810.90188381140.96131810561.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0106649951
GSE13712_SHEARDown-0.1319042339
GSE13712_STATICDown-0.1386019772
GSE19018Up0.1100270021
GSE19899_A1Up0.0527542924
GSE19899_A2Down-0.0073233785
PubMed_21979375_A1Down-0.0864956486
PubMed_21979375_A2Down-0.0744527684
GSE35957Up0.0854991127
GSE36640Up0.0123446342
GSE54402Down-0.0009932015
GSE9593Up0.1243791969
GSE43922Up0.3412546950
GSE24585Up0.3982068028
GSE37065Down-0.1423075906
GSE28863_A1Up0.1889885408
GSE28863_A2Up0.1199580383
GSE28863_A3Up0.3993276936
GSE28863_A4Up0.1153882783
GSE48662Down-0.0326244620

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.