HCSGD entry for MAZ
1. General information
| Official gene symbol | MAZ |
|---|---|
| Entrez ID | 4150 |
| Gene full name | MYC-associated zinc finger protein (purine-binding transcription factor) |
| Other gene symbols | PUR1 Pur-1 SAF-1 SAF-2 SAF-3 ZF87 ZNF801 Zif87 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding | IDA | molecular_function |
| GO:0000981 | Sequence-specific DNA binding RNA polymerase II transcription factor activity | IEA | molecular_function |
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003682 | Chromatin binding | IEA | molecular_function |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006367 | Transcription initiation from RNA polymerase II promoter | IDA | biological_process |
| GO:0006369 | Termination of RNA polymerase II transcription | IDA | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9667791535 | 0.0301729076 | 0.9999902473 | 0.3279030140 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1593949734 |
| GSE13712_SHEAR | Down | -0.4787070749 |
| GSE13712_STATIC | Down | -0.4593380982 |
| GSE19018 | Down | -0.2841500975 |
| GSE19899_A1 | Down | -0.1584821905 |
| GSE19899_A2 | Up | 0.0556020186 |
| PubMed_21979375_A1 | Down | -0.1485578389 |
| PubMed_21979375_A2 | Up | 0.2375617011 |
| GSE35957 | Down | -0.3557325350 |
| GSE36640 | Down | -1.0600138500 |
| GSE54402 | Up | 0.0384768300 |
| GSE9593 | Down | -0.2087548346 |
| GSE43922 | Up | 0.1127608336 |
| GSE24585 | Down | -0.5650326563 |
| GSE37065 | Down | -0.3033052000 |
| GSE28863_A1 | Down | -0.1712334177 |
| GSE28863_A2 | Down | -0.1104564051 |
| GSE28863_A3 | Down | -0.2378077778 |
| GSE28863_A4 | Down | -0.1229044608 |
| GSE48662 | Up | 0.1948828682 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-148b-3p | MIMAT0000759 | MIRT019432 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT023060 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-122-5p | MIMAT0000421 | MIRT023351 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-1180-3p | MIMAT0005825 | MIRT035938 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT037070 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040168 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041430 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-5p | MIMAT0000761 | MIRT043202 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-326 | MIMAT0000756 | MIRT043629 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046789 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-181a-5p | MIMAT0000256 | MIRT047310 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30d-5p | MIMAT0000245 | MIRT047788 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
