HCSGD entry for MARS


1. General information

Official gene symbolMARS
Entrez ID4141
Gene full namemethionyl-tRNA synthetase
Other gene symbolsMETRS MRS MTRNS
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000049TRNA bindingIEAmolecular_function
GO:0004812Aminoacyl-tRNA ligase activityIEAmolecular_function
GO:0004825Methionine-tRNA ligase activityIEA TASmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005737CytoplasmIDA IEAcellular_component
GO:0005739MitochondrionIEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006418TRNA aminoacylation for protein translationIEA TASbiological_process
GO:0006431Methionyl-tRNA aminoacylationIEAbiological_process
GO:0010467Gene expressionTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.11500336230.99686695410.69698445771.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954--
GSE13712_SHEAR--
GSE13712_STATIC--
GSE19018--
GSE19899_A1--
GSE19899_A2--
PubMed_21979375_A1--
PubMed_21979375_A2--
GSE35957--
GSE36640--
GSE54402--
GSE9593--
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.2114004651

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-16-5pMIMAT0000069MIRT031964ProteomicsFunctional MTI (Weak)18668040
hsa-let-7b-5pMIMAT0000063MIRT032489ProteomicsFunctional MTI (Weak)18668040
hsa-miR-505-5pMIMAT0004776MIRT037977CLASHFunctional MTI (Weak)23622248
hsa-miR-296-3pMIMAT0004679MIRT038386CLASHFunctional MTI (Weak)23622248
hsa-miR-615-3pMIMAT0003283MIRT040324CLASHFunctional MTI (Weak)23622248
hsa-miR-193b-3pMIMAT0002819MIRT041304CLASHFunctional MTI (Weak)23622248
hsa-miR-484MIMAT0002174MIRT042166CLASHFunctional MTI (Weak)23622248
hsa-miR-339-5pMIMAT0000764MIRT042790CLASHFunctional MTI (Weak)23622248
hsa-miR-185-5pMIMAT0000455MIRT045372CLASHFunctional MTI (Weak)23622248
hsa-miR-222-3pMIMAT0000279MIRT046729CLASHFunctional MTI (Weak)23622248
hsa-miR-10a-5pMIMAT0000253MIRT047668CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049733CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.