HCSGD entry for MARK1

1. General information

Official gene symbolMARK1
Entrez ID4139
Gene full nameMAP/microtubule affinity-regulating kinase 1
Other gene symbolsMARK Par-1c Par1c
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000226Microtubule cytoskeleton organizationIEAbiological_process
GO:0000287Magnesium ion bindingIDAmolecular_function
GO:0001764Neuron migrationISSbiological_process
GO:0001786Phosphatidylserine bindingIDAmolecular_function
GO:0004674Protein serine/threonine kinase activityIDAmolecular_function
GO:0005524ATP bindingIDAmolecular_function
GO:0005546Phosphatidylinositol-4,5-bisphosphate bindingIDAmolecular_function
GO:0005737CytoplasmISScellular_component
GO:0005856CytoskeletonISScellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0006468Protein phosphorylationIDAbiological_process
GO:0007010Cytoskeleton organizationISSbiological_process
GO:0015630Microtubule cytoskeletonTAScellular_component
GO:0016055Wnt signaling pathwayIEAbiological_process
GO:0035556Intracellular signal transductionIDAbiological_process
GO:0050321Tau-protein kinase activityISSmolecular_function
GO:0070300Phosphatidic acid bindingIDAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.88024056460.41483853200.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0288344154
GSE13712_SHEARDown-0.3710515262
GSE13712_STATICDown-0.2671521968
GSE19018Up0.1868956388
GSE19899_A1Up0.1129754435
GSE19899_A2Up0.0459713659
PubMed_21979375_A1Up0.0178646076
PubMed_21979375_A2Up0.0744862662
GSE35957Up0.1337417976
GSE36640Up0.0531578077
GSE54402Up0.1001757078
GSE9593Down-0.3837727073
GSE43922Up0.0191538524
GSE24585Up0.0625538346
GSE37065Down-0.3945210801
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.1591528654

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.