HCSGD entry for MAP4
1. General information
| Official gene symbol | MAP4 |
|---|---|
| Entrez ID | 4134 |
| Gene full name | microtubule-associated protein 4 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005198 | Structural molecule activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005874 | Microtubule | IEA | cellular_component |
| GO:0005875 | Microtubule associated complex | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0007052 | Mitotic spindle organization | IMP | biological_process |
| GO:0008017 | Microtubule binding | IEA | molecular_function |
| GO:0015630 | Microtubule cytoskeleton | IDA | cellular_component |
| GO:0051012 | Microtubule sliding | IMP | biological_process |
| GO:0051294 | Establishment of spindle orientation | IGI IMP | biological_process |
| GO:0051301 | Cell division | IMP | biological_process |
| GO:0072686 | Mitotic spindle | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7924798222 | 0.0743359523 | 0.9999902473 | 0.5138391019 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2897855302 |
| GSE13712_SHEAR | Up | 0.0999136363 |
| GSE13712_STATIC | Up | 0.1428012643 |
| GSE19018 | Up | 0.3185495043 |
| GSE19899_A1 | Down | -0.3574065185 |
| GSE19899_A2 | Down | -0.5104916080 |
| PubMed_21979375_A1 | Down | -0.8292194869 |
| PubMed_21979375_A2 | Down | -0.2709576256 |
| GSE35957 | Down | -0.0046316233 |
| GSE36640 | Up | 0.2555112029 |
| GSE54402 | Down | -0.3447760708 |
| GSE9593 | Up | 0.3612858668 |
| GSE43922 | Down | -0.1356204894 |
| GSE24585 | Down | -0.1876438961 |
| GSE37065 | Down | -0.2351078427 |
| GSE28863_A1 | Up | 0.2845654085 |
| GSE28863_A2 | Up | 0.2709258773 |
| GSE28863_A3 | Down | -0.1299470275 |
| GSE28863_A4 | Down | -0.3896055439 |
| GSE48662 | Up | 0.1999986884 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Docetaxel | DB01248 | APRD00932 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025500 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027147 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031936 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031936 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-551b-3p | MIMAT0003233 | MIRT040524 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT042202 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-339-5p | MIMAT0000764 | MIRT042741 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043550 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-328-3p | MIMAT0000752 | MIRT043764 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-23b-3p | MIMAT0000418 | MIRT046357 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-196a-5p | MIMAT0000226 | MIRT048277 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-100-5p | MIMAT0000098 | MIRT048440 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049316 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052234 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
