HCSGD entry for ASIC1
1. General information
| Official gene symbol | ASIC1 |
|---|---|
| Entrez ID | 41 |
| Gene full name | acid-sensing (proton-gated) ion channel 1 |
| Other gene symbols | ACCN2 ASIC BNaC2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001101 | Response to acid | IEA | biological_process |
| GO:0005272 | Sodium channel activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | IEA | cellular_component |
| GO:0006810 | Transport | TAS | biological_process |
| GO:0006814 | Sodium ion transport | NAS | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007613 | Memory | IEA | biological_process |
| GO:0008306 | Associative learning | IEA | biological_process |
| GO:0009268 | Response to pH | TAS | biological_process |
| GO:0009986 | Cell surface | IEA | cellular_component |
| GO:0015280 | Ligand-gated sodium channel activity | IEA | molecular_function |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0022839 | Ion gated channel activity | IEA | molecular_function |
| GO:0034220 | Ion transmembrane transport | TAS | biological_process |
| GO:0035725 | Sodium ion transmembrane transport | TAS | biological_process |
| GO:0042391 | Regulation of membrane potential | IEA | biological_process |
| GO:0045202 | Synapse | IEA | cellular_component |
| GO:0046929 | Negative regulation of neurotransmitter secretion | IEA | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
| GO:0070588 | Calcium ion transmembrane transport | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9699428821 | 0.0458516318 | 0.9999902473 | 0.4016862230 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1405169005 |
| GSE13712_SHEAR | Down | -0.0861979393 |
| GSE13712_STATIC | Up | 0.0527032949 |
| GSE19018 | Up | 0.1398718286 |
| GSE19899_A1 | Down | -0.0228171195 |
| GSE19899_A2 | Down | -0.1861988414 |
| PubMed_21979375_A1 | Down | -0.6627935301 |
| PubMed_21979375_A2 | Down | -0.4143612886 |
| GSE35957 | Down | -0.0818495282 |
| GSE36640 | Up | 0.1393920144 |
| GSE54402 | Down | -0.4808536155 |
| GSE9593 | Down | -0.0945722745 |
| GSE43922 | Down | -1.1709791728 |
| GSE24585 | Down | -0.2555258340 |
| GSE37065 | Down | -0.3896620551 |
| GSE28863_A1 | Up | 0.1610097906 |
| GSE28863_A2 | Down | -0.0772787980 |
| GSE28863_A3 | Up | 0.2105509136 |
| GSE28863_A4 | Down | -0.0600597057 |
| GSE48662 | Down | -0.2856047201 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7b-5p | MIMAT0000063 | MIRT052268 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
