HCSGD entry for SMAD9

1. General information

Official gene symbolSMAD9
Entrez ID4093
Gene full nameSMAD family member 9
Other gene symbolsMADH6 MADH9 SMAD8 SMAD8A SMAD8B
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001657Ureteric bud developmentIEAbiological_process
GO:0001666Response to hypoxiaIEAbiological_process
GO:0001880Mullerian duct regressionIEAbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005622IntracellularTAScellular_component
GO:0005634NucleusTAScellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005667Transcription factor complexIEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006468Protein phosphorylationIEAbiological_process
GO:0007179Transforming growth factor beta receptor signaling pathwayIEAbiological_process
GO:0030509BMP signaling pathwayTASbiological_process
GO:0030618Transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activityTASmolecular_function
GO:0030901Midbrain developmentIEAbiological_process
GO:0030902Hindbrain developmentIEAbiological_process
GO:0035556Intracellular signal transductionTASbiological_process
GO:0045597Positive regulation of cell differentiationIEAbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0051216Cartilage developmentIEAbiological_process
GO:0060348Bone developmentIEAbiological_process
GO:0071407Cellular response to organic cyclic compoundIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.99021395840.00089948710.99999024730.0566338902

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.6387251029
GSE13712_SHEARDown-0.6713926493
GSE13712_STATICDown-0.1359959053
GSE19018Down-0.4411543328
GSE19899_A1Down-0.9473250834
GSE19899_A2Down-1.8332859363
PubMed_21979375_A1Down-2.0271311826
PubMed_21979375_A2Down-3.2129673676
GSE35957Down-0.0170540254
GSE36640Up0.5353484427
GSE54402Down-1.0695662775
GSE9593Down-1.1969413603
GSE43922Down-1.1160190022
GSE24585Up0.1149777948
GSE37065Down-0.0460595793
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.0275050010

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-106b-5pMIMAT0000680MIRT020446MicroarrayFunctional MTI (Weak)17242205
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.