HCSGD entry for MIR212

1. General information

Official gene symbolMIR212
Entrez ID406994
Gene full namemicroRNA 212
Other gene symbolsMIRN212 mir-212
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

Not in the Gene ontology

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.78090993880.63024940920.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954--
GSE13712_SHEAR--
GSE13712_STATIC--
GSE19018--
GSE19899_A1--
GSE19899_A2--
PubMed_21979375_A1--
PubMed_21979375_A2--
GSE35957--
GSE36640--
GSE54402--
GSE9593--
GSE43922Up0.1344112809
GSE24585Up0.0761064932
GSE37065Down-0.0287076370
GSE28863_A1Up0.0098628119
GSE28863_A2Up0.2003083697
GSE28863_A3Up0.1245359744
GSE28863_A4Down-0.3175241912
GSE48662--

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 2 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

26439987In this study, we found that miR-212 is downregulated in PCa tissues when compared with benign adjacent regions (n = 40)
26439987Also, we observed reduced levels of circulatory miR-212 in serum from PCa patients (n = 40) when compared with healthy controls (n = 32)
26439987Elucidating the functional role of miR-212, we demonstrate that miR-212 negatively modulates starvation induced autophagy in PCa cells by targeting sirtuin 1 (SIRT1)
26439987Overexpression of miR-212 also leads to inhibition of angiogenesis and cellular senescence
26439987In conclusion, our study indicates a functional role of miR-212 in PCa and suggests the development of miR-212 based therapies
23922798RESULTS: The expression of RBP2 was stronger in cancerous than non-cancerous tissues, but that of its binding microRNA, Homo sapiens miR-212 (hsa-miR-212), showed an opposite pattern
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