HCSGD entry for SH2D1A
1. General information
| Official gene symbol | SH2D1A |
|---|---|
| Entrez ID | 4068 |
| Gene full name | SH2 domain containing 1A |
| Other gene symbols | DSHP EBVS IMD5 LYP MTCP1 SAP SAP/SH2D1A XLP XLPD |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005070 | SH3/SH2 adaptor activity | NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006959 | Humoral immune response | IEA | biological_process |
| GO:0006968 | Cellular defense response | NAS | biological_process |
| GO:0007267 | Cell-cell signaling | IDA | biological_process |
| GO:0009967 | Positive regulation of signal transduction | NAS | biological_process |
| GO:0045954 | Positive regulation of natural killer cell mediated cytotoxicity | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6740992781 | 0.9259570571 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0248306055 |
| GSE13712_SHEAR | Up | 0.0505759265 |
| GSE13712_STATIC | Up | 0.0756888161 |
| GSE19018 | Up | 0.0197212462 |
| GSE19899_A1 | Up | 0.1216767941 |
| GSE19899_A2 | Down | -0.0463275547 |
| PubMed_21979375_A1 | Up | 0.1920878539 |
| PubMed_21979375_A2 | Up | 0.0795586849 |
| GSE35957 | Up | 0.0704733006 |
| GSE36640 | Up | 0.0168768187 |
| GSE54402 | Up | 0.0343618489 |
| GSE9593 | Up | 0.0403524223 |
| GSE43922 | Up | 0.0087191115 |
| GSE24585 | Down | -0.1124323464 |
| GSE37065 | Up | 0.1250780443 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.0099799173 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-142-3p | MIMAT0000434 | MIRT021557 | Microarray | Functional MTI (Weak) | 17612493 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
