HCSGD entry for LTBP3
1. General information
| Official gene symbol | LTBP3 |
|---|---|
| Entrez ID | 4054 |
| Gene full name | latent transforming growth factor beta binding protein 3 |
| Other gene symbols | LTBP-3 LTBP2 STHAG6 pp6425 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005576 | Extracellular region | IEA TAS | cellular_component |
| GO:0007179 | Transforming growth factor beta receptor signaling pathway | IEA | biological_process |
| GO:0019838 | Growth factor binding | IEA | molecular_function |
| GO:0030198 | Extracellular matrix organization | TAS | biological_process |
| GO:0030502 | Negative regulation of bone mineralization | IEA | biological_process |
| GO:0032331 | Negative regulation of chondrocyte differentiation | IEA | biological_process |
| GO:0045780 | Positive regulation of bone resorption | IEA | biological_process |
| GO:0046849 | Bone remodeling | IEA | biological_process |
| GO:0060349 | Bone morphogenesis | IEA | biological_process |
| GO:0060430 | Lung saccule development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2709176589 | 0.4723715094 | 0.9680727260 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0428237764 |
| GSE13712_SHEAR | Down | -0.3190983835 |
| GSE13712_STATIC | Down | -0.2054821037 |
| GSE19018 | Up | 0.0852644311 |
| GSE19899_A1 | Down | -0.3954792989 |
| GSE19899_A2 | Up | 0.0894266968 |
| PubMed_21979375_A1 | Down | -0.3043895683 |
| PubMed_21979375_A2 | Up | 0.1226054144 |
| GSE35957 | Down | -0.3338682205 |
| GSE36640 | Up | 0.2939272906 |
| GSE54402 | Down | -0.2335499347 |
| GSE9593 | Down | -0.1282254176 |
| GSE43922 | Up | 0.0209761978 |
| GSE24585 | Up | 0.3076655324 |
| GSE37065 | Down | -0.1881641387 |
| GSE28863_A1 | Up | 0.5729496924 |
| GSE28863_A2 | Up | 0.3840205433 |
| GSE28863_A3 | Up | 0.3515919518 |
| GSE28863_A4 | Up | 0.0475061648 |
| GSE48662 | Up | 0.4768618332 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1249 | MIMAT0005901 | MIRT035867 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040731 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045534 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
