HCSGD entry for LTBP1
1. General information
| Official gene symbol | LTBP1 |
|---|---|
| Entrez ID | 4052 |
| Gene full name | latent transforming growth factor beta binding protein 1 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005024 | Transforming growth factor beta-activated receptor activity | NAS | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005578 | Proteinaceous extracellular matrix | IEA NAS | cellular_component |
| GO:0006468 | Protein phosphorylation | NAS | biological_process |
| GO:0007165 | Signal transduction | NAS | biological_process |
| GO:0007178 | Transmembrane receptor protein serine/threonine kinase signaling pathway | NAS | biological_process |
| GO:0008152 | Metabolic process | NAS | biological_process |
| GO:0016310 | Phosphorylation | NAS | biological_process |
| GO:0019838 | Growth factor binding | IEA | molecular_function |
| GO:0030198 | Extracellular matrix organization | TAS | biological_process |
| GO:0031012 | Extracellular matrix | IDA | cellular_component |
| GO:0035583 | Sequestering of TGFbeta in extracellular matrix | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5557100490 | 0.0036495422 | 0.9999902473 | 0.1226814815 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.6028294493 |
| GSE13712_SHEAR | Down | -0.9786677897 |
| GSE13712_STATIC | Down | -0.2766599081 |
| GSE19018 | Up | 0.0377930217 |
| GSE19899_A1 | Down | -1.2193207568 |
| GSE19899_A2 | Down | -1.3582665614 |
| PubMed_21979375_A1 | Down | -1.7620522027 |
| PubMed_21979375_A2 | Down | -0.9784412355 |
| GSE35957 | Down | -0.5155768061 |
| GSE36640 | Up | 0.1461459018 |
| GSE54402 | Down | -0.4350303289 |
| GSE9593 | Up | 0.7162032634 |
| GSE43922 | Down | -0.6654179282 |
| GSE24585 | Down | -0.8421189372 |
| GSE37065 | Up | 0.1528655249 |
| GSE28863_A1 | Up | 0.6668836693 |
| GSE28863_A2 | Up | 1.2508436657 |
| GSE28863_A3 | Down | -0.1204055198 |
| GSE28863_A4 | Up | 0.0596994175 |
| GSE48662 | Down | -0.4935282004 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017091 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049456 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
