HCSGD entry for LRP2

1. General information

Official gene symbolLRP2
Entrez ID4036
Gene full namelow density lipoprotein receptor-related protein 2
Other gene symbolsDBS GP330
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001523Retinoid metabolic processTASbiological_process
GO:0005509Calcium ion bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005764LysosomeTAScellular_component
GO:0005765Lysosomal membraneIDAcellular_component
GO:0005768EndosomeIEAcellular_component
GO:0005783Endoplasmic reticulumIEAcellular_component
GO:0005794Golgi apparatusIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005905Coated pitIEAcellular_component
GO:0006486Protein glycosylationTASbiological_process
GO:0006629Lipid metabolic processTASbiological_process
GO:0006897EndocytosisTASbiological_process
GO:0006898Receptor-mediated endocytosisIEAbiological_process
GO:0007603Phototransduction, visible lightTASbiological_process
GO:0008202Steroid metabolic processTASbiological_process
GO:0008283Cell proliferationIEAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0016324Apical plasma membraneISScellular_component
GO:0017124SH3 domain bindingIEAmolecular_function
GO:0030139Endocytic vesicleIEAcellular_component
GO:0030900Forebrain developmentIEAbiological_process
GO:0031526Brush border membraneIEAcellular_component
GO:0042359Vitamin D metabolic processTASbiological_process
GO:0043235Receptor complexIDAcellular_component
GO:0044281Small molecule metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.56316305610.76738629230.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1001145670
GSE13712_SHEARDown-0.0543326353
GSE13712_STATICDown-0.0479424226
GSE19018Up0.0873022197
GSE19899_A1Up0.1342520848
GSE19899_A2Up0.1673127559
PubMed_21979375_A1Down-0.1057679838
PubMed_21979375_A2Down-0.0345616003
GSE35957Up0.3711556064
GSE36640Up0.0582396954
GSE54402Down-0.1029093719
GSE9593Up0.0557768034
GSE43922Up0.0136828369
GSE24585Down-0.5788400272
GSE37065Down-0.0591749460
GSE28863_A1Down-0.0276106797
GSE28863_A2Up0.0577756382
GSE28863_A3Up0.1659480661
GSE28863_A4Up0.0638748664
GSE48662Up0.4882124091

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

UrokinaseDB00013 BTD00030 | BIOD00030
Insulin PorkDB00071 BTD00031 | BIOD00031
GentamicinDB00798 APRD00214

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-196a-5pMIMAT0000226MIRT048169CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.