HCSGD entry for ARL3
1. General information
| Official gene symbol | ARL3 |
|---|---|
| Entrez ID | 403 |
| Gene full name | ADP-ribosylation factor-like 3 |
| Other gene symbols | ARFL3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | IEA | cellular_component |
| GO:0000910 | Cytokinesis | IMP | biological_process |
| GO:0001822 | Kidney development | ISS | biological_process |
| GO:0003924 | GTPase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005525 | GTP binding | IDA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0005876 | Spindle microtubule | IDA | cellular_component |
| GO:0005881 | Cytoplasmic microtubule | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006892 | Post-Golgi vesicle-mediated transport | IMP | biological_process |
| GO:0007264 | Small GTPase mediated signal transduction | IDA | biological_process |
| GO:0008017 | Microtubule binding | IDA | molecular_function |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0019003 | GDP binding | IDA | molecular_function |
| GO:0030496 | Midbody | IDA | cellular_component |
| GO:0032391 | Photoreceptor connecting cilium | IDA | cellular_component |
| GO:0042073 | Intraciliary transport | IEA | biological_process |
| GO:0042461 | Photoreceptor cell development | ISS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0060271 | Cilium morphogenesis | IMP | biological_process |
| GO:0072372 | Primary cilium | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9477989210 | 0.1905383800 | 0.9999902473 | 0.8462101738 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0849570060 |
| GSE13712_SHEAR | Down | -0.2013546032 |
| GSE13712_STATIC | Down | -0.2243989608 |
| GSE19018 | Up | 0.4807533432 |
| GSE19899_A1 | Down | -0.0531085781 |
| GSE19899_A2 | Down | -0.0864860238 |
| PubMed_21979375_A1 | Down | -0.3912923877 |
| PubMed_21979375_A2 | Down | -0.1711077879 |
| GSE35957 | Down | -0.2225087280 |
| GSE36640 | Down | -0.3526091058 |
| GSE54402 | Down | -0.1265876334 |
| GSE9593 | Down | -0.1480179934 |
| GSE43922 | Up | 0.0395556951 |
| GSE24585 | Down | -0.1551993581 |
| GSE37065 | Down | -0.0762109227 |
| GSE28863_A1 | Up | 0.0461131512 |
| GSE28863_A2 | Down | -0.1916530508 |
| GSE28863_A3 | Down | -0.2124169068 |
| GSE28863_A4 | Up | 0.0487294734 |
| GSE48662 | Up | 0.3177571317 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| 2-(N-Morpholino)-Ethanesulfonic Acid | DB03814 | EXPT02154 |
| Guanosine-5'-Diphosphate | DB04315 | EXPT01573 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027108 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031723 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
