HCSGD entry for ARL1
1. General information
| Official gene symbol | ARL1 |
|---|---|
| Entrez ID | 400 |
| Gene full name | ADP-ribosylation factor-like 1 |
| Other gene symbols | ARFL1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | IEA | cellular_component |
| GO:0003924 | GTPase activity | IDA | molecular_function |
| GO:0005525 | GTP binding | IDA IEA | molecular_function |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA ISS | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0005802 | Trans-Golgi network | IEA ISS | cellular_component |
| GO:0006184 | GTP catabolic process | IDA | biological_process |
| GO:0007030 | Golgi organization | IEA ISS | biological_process |
| GO:0007264 | Small GTPase mediated signal transduction | IEA | biological_process |
| GO:0008047 | Enzyme activator activity | IDA | molecular_function |
| GO:0009404 | Toxin metabolic process | IDA | biological_process |
| GO:0019904 | Protein domain specific binding | IPI | molecular_function |
| GO:0031584 | Activation of phospholipase D activity | IDA | biological_process |
| GO:0034067 | Protein localization to Golgi apparatus | IMP | biological_process |
| GO:0042147 | Retrograde transport, endosome to Golgi | IMP | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0048193 | Golgi vesicle transport | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3945247977 | 0.2573616010 | 0.9999902473 | 0.9724396641 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3005009664 |
| GSE13712_SHEAR | Down | -0.1115937554 |
| GSE13712_STATIC | Down | -0.0167163885 |
| GSE19018 | Up | 0.0833702319 |
| GSE19899_A1 | Down | -0.2747014082 |
| GSE19899_A2 | Down | -0.4679651751 |
| PubMed_21979375_A1 | Down | -0.3411247879 |
| PubMed_21979375_A2 | Down | -0.5021277554 |
| GSE35957 | Up | 0.0756326752 |
| GSE36640 | Up | 0.6696615658 |
| GSE54402 | Down | -0.1806532833 |
| GSE9593 | Up | 0.2362270626 |
| GSE43922 | Down | -0.1429920638 |
| GSE24585 | Up | 0.0123916829 |
| GSE37065 | Up | 0.2144427328 |
| GSE28863_A1 | Up | 0.1017343963 |
| GSE28863_A2 | Up | 0.0999075817 |
| GSE28863_A3 | Down | -0.6984175843 |
| GSE28863_A4 | Up | 0.3175131442 |
| GSE48662 | Up | 0.2011902990 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Guanosine-5'-Diphosphate | DB04315 | EXPT01573 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020262 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT028155 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-24-3p | MIMAT0000080 | MIRT030486 | Microarray | Functional MTI (Weak) | 19748357 |
| hsa-miR-769-5p | MIMAT0003886 | MIRT039171 | CLASH | Functional MTI (Weak) | 23622248 |
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