HCSGD entry for LMAN1

1. General information

Official gene symbolLMAN1
Entrez ID3998
Gene full namelectin, mannose-binding, 1
Other gene symbolsERGIC-53 ERGIC53 F5F8D FMFD1 MCFD1 MR60 gp58
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000139Golgi membraneIEAcellular_component
GO:0005515Protein bindingIPImolecular_function
GO:0005537Mannose bindingTASmolecular_function
GO:0005789Endoplasmic reticulum membraneIEAcellular_component
GO:0005793Endoplasmic reticulum-Golgi intermediate compartmentIDAcellular_component
GO:0006457Protein foldingTASbiological_process
GO:0006888ER to Golgi vesicle-mediated transportTASbiological_process
GO:0007029Endoplasmic reticulum organizationIEAbiological_process
GO:0007030Golgi organizationIMPbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0010638Positive regulation of organelle organizationIMPbiological_process
GO:0012507ER to Golgi transport vesicle membraneTAScellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0018279Protein N-linked glycosylation via asparagineTASbiological_process
GO:0030017SarcomereIEAcellular_component
GO:0032527Protein exit from endoplasmic reticulumIMPbiological_process
GO:0033116Endoplasmic reticulum-Golgi intermediate compartment membraneIEAcellular_component
GO:0034498Early endosome to Golgi transportIMPbiological_process
GO:0043687Post-translational protein modificationTASbiological_process
GO:0044267Cellular protein metabolic processTASbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0051082Unfolded protein bindingTASmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.41737771740.06899435050.99999024730.4953628751

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.3970950049
GSE13712_SHEARDown-0.1892870726
GSE13712_STATICUp0.0125626863
GSE19018Up0.5449752914
GSE19899_A1Down-0.6386933893
GSE19899_A2Down-0.6853859863
PubMed_21979375_A1Down-1.1109557746
PubMed_21979375_A2Down-1.4787109373
GSE35957Up0.1838679269
GSE36640Down-0.0730343217
GSE54402Down-0.1403617754
GSE9593Up0.2623373827
GSE43922Down-0.0259785389
GSE24585Down-0.2328378081
GSE37065Down-0.0782808204
GSE28863_A1Up0.3060101858
GSE28863_A2Up0.3437432943
GSE28863_A3Down-0.0497124074
GSE28863_A4Up0.2262578174
GSE48662Up0.3218718949

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-215-5pMIMAT0000272MIRT024823MicroarrayFunctional MTI (Weak)19074876
hsa-miR-192-5pMIMAT0000222MIRT026376MicroarrayFunctional MTI (Weak)19074876
hsa-miR-18a-3pMIMAT0002891MIRT040889CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

23466301These genes, PDIA3, WDR1, FSTL1, COPG1, LMAN1, and PDIA6, significantly downregulated
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