HCSGD entry for LLGL2


1. General information

Official gene symbolLLGL2
Entrez ID3993
Gene full namelethal giant larvae homolog 2 (Drosophila)
Other gene symbolsHGL LGL2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0006887ExocytosisIEAbiological_process
GO:0007049Cell cycleIEAbiological_process
GO:0030165PDZ domain bindingIPImolecular_function
GO:0032878Regulation of establishment or maintenance of cell polarityIDAbiological_process
GO:0043231Intracellular membrane-bounded organelleIDAcellular_component
GO:0051301Cell divisionIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.57462515480.78845538160.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0635278585
GSE13712_SHEARDown-0.6300160966
GSE13712_STATICDown-0.1088675849
GSE19018Up0.0368386600
GSE19899_A1Up0.0629187622
GSE19899_A2Down-0.0748158494
PubMed_21979375_A1Up0.0230791296
PubMed_21979375_A2Up0.0115326374
GSE35957Up0.1853179031
GSE36640Up0.1342939012
GSE54402Up0.0674626986
GSE9593Down-0.0378505110
GSE43922Up0.0368066527
GSE24585Up0.1672022333
GSE37065Up0.0829653586
GSE28863_A1Down-0.1275920390
GSE28863_A2Down-0.1006246944
GSE28863_A3Up0.3589606773
GSE28863_A4Up0.1678874792
GSE48662Up0.0769593827

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018037MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.