HCSGD entry for FADS1

1. General information

Official gene symbolFADS1
Entrez ID3992
Gene full namefatty acid desaturase 1
Other gene symbolsD5D FADS6 FADSD5 LLCDL1 TU12
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000248C-5 sterol desaturase activityTASmolecular_function
GO:0005506Iron ion bindingIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005739MitochondrionIEAcellular_component
GO:0005789Endoplasmic reticulum membraneTAScellular_component
GO:0006355Regulation of transcription, DNA-templatedNASbiological_process
GO:0006629Lipid metabolic processIEAbiological_process
GO:0006636Unsaturated fatty acid biosynthetic processIDA IEAbiological_process
GO:0007267Cell-cell signalingNASbiological_process
GO:0007568AgingIEAbiological_process
GO:0008654Phospholipid biosynthetic processTASbiological_process
GO:0009267Cellular response to starvationIDAbiological_process
GO:0009744Response to sucroseIEAbiological_process
GO:0014070Response to organic cyclic compoundIEAbiological_process
GO:0016020MembraneNAScellular_component
GO:0016021Integral component of membraneNAScellular_component
GO:0016491Oxidoreductase activityIDAmolecular_function
GO:0016717Oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of waterIEAmolecular_function
GO:0019369Arachidonic acid metabolic processIEAbiological_process
GO:0020037Heme bindingIEAmolecular_function
GO:0032868Response to insulinIEAbiological_process
GO:0033189Response to vitamin AIEAbiological_process
GO:0033559Unsaturated fatty acid metabolic processTASbiological_process
GO:0036109Alpha-linolenic acid metabolic processTASbiological_process
GO:0043231Intracellular membrane-bounded organelleNAScellular_component
GO:0043651Linoleic acid metabolic processTASbiological_process
GO:0044255Cellular lipid metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045595Regulation of cell differentiationNASbiological_process
GO:0046456Icosanoid biosynthetic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.39784786290.97931145470.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954--
GSE13712_SHEAR--
GSE13712_STATIC--
GSE19018--
GSE19899_A1--
GSE19899_A2--
PubMed_21979375_A1--
PubMed_21979375_A2--
GSE35957--
GSE36640--
GSE54402--
GSE9593--
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.2003215950

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-155-5pMIMAT0000646MIRT001549pSILAC//Proteomics;OtherFunctional MTI (Weak)18668040
hsa-miR-335-5pMIMAT0000765MIRT018342MicroarrayFunctional MTI (Weak)18185580
hsa-miR-1MIMAT0000416MIRT023902ProteomicsFunctional MTI (Weak)18668040
hsa-miR-215-5pMIMAT0000272MIRT024788MicroarrayFunctional MTI (Weak)19074876
hsa-miR-192-5pMIMAT0000222MIRT026611MicroarrayFunctional MTI (Weak)19074876
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.