HCSGD entry for LIM2
1. General information
| Official gene symbol | LIM2 |
|---|---|
| Entrez ID | 3982 |
| Gene full name | lens intrinsic membrane protein 2, 19kDa |
| Other gene symbols | MP17 MP19 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002088 | Lens development in camera-type eye | IEA | biological_process |
| GO:0005212 | Structural constituent of eye lens | IEA | molecular_function |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0007043 | Cell-cell junction assembly | NAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030054 | Cell junction | NAS | cellular_component |
| GO:0031982 | Vesicle | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1932634968 | 0.9332916113 | 0.8523606736 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0503018787 |
| GSE13712_SHEAR | Up | 0.1601122685 |
| GSE13712_STATIC | Down | -0.0586672835 |
| GSE19018 | Down | -0.0341917142 |
| GSE19899_A1 | Up | 0.0809595236 |
| GSE19899_A2 | Up | 0.0531859291 |
| PubMed_21979375_A1 | Up | 0.3734301801 |
| PubMed_21979375_A2 | Up | 0.0432527338 |
| GSE35957 | Down | -0.0597263336 |
| GSE36640 | Up | 0.0313631870 |
| GSE54402 | Down | -0.0358270535 |
| GSE9593 | Down | -0.0954852022 |
| GSE43922 | Up | 0.1910632866 |
| GSE24585 | Up | 0.1720337382 |
| GSE37065 | Down | -0.1580508167 |
| GSE28863_A1 | Up | 0.0548386953 |
| GSE28863_A2 | Up | 0.0322409992 |
| GSE28863_A3 | Up | 0.4683296169 |
| GSE28863_A4 | Up | 0.4553792403 |
| GSE48662 | Up | 0.0301207626 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018500 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
