HCSGD entry for LGALS9
1. General information
| Official gene symbol | LGALS9 |
|---|---|
| Entrez ID | 3965 |
| Gene full name | lectin, galactoside-binding, soluble, 9 |
| Other gene symbols | HUAT LGALS9A |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004871 | Signal transducer activity | IMP | molecular_function |
| GO:0005534 | Galactose binding | TAS | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0007165 | Signal transduction | IMP | biological_process |
| GO:0030246 | Carbohydrate binding | IDA IEA | molecular_function |
| GO:0043123 | Positive regulation of I-kappaB kinase/NF-kappaB signaling | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1608405646 | 0.3032340982 | 0.7951118784 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0470682825 |
| GSE13712_SHEAR | Up | 0.5886994974 |
| GSE13712_STATIC | Up | 1.3101450033 |
| GSE19018 | Up | 0.0360838963 |
| GSE19899_A1 | Down | -0.0685847704 |
| GSE19899_A2 | Down | -0.1685305238 |
| PubMed_21979375_A1 | Down | -0.2179004432 |
| PubMed_21979375_A2 | Down | -0.0334541401 |
| GSE35957 | Down | -0.1123660495 |
| GSE36640 | Up | 0.1459881406 |
| GSE54402 | Up | 0.0063351906 |
| GSE9593 | Up | 0.3014300491 |
| GSE43922 | Down | -0.4024436462 |
| GSE24585 | Down | -0.6557882148 |
| GSE37065 | Up | 0.8379573922 |
| GSE28863_A1 | Up | 0.0521495621 |
| GSE28863_A2 | Up | 0.1414134225 |
| GSE28863_A3 | Up | 0.1397824533 |
| GSE28863_A4 | Down | -0.0045204931 |
| GSE48662 | Up | 0.1140256263 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| (R)-1-Para-Nitro-Phenyl-2-Azido-Ethanol | DB04472 | EXPT02812 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017245 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 22505239 | UNLABELLED: The interaction between T cell immunoglobulin mucin-domain-containing molecule (Tim-3) expressed on T helper 1 (Th1) cells, and its ligand, galectin-9, negatively regulates Th1-mediated immune responses |
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