HCSGD entry for ARHGDIA

1. General information

Official gene symbolARHGDIA
Entrez ID396
Gene full nameRho GDP dissociation inhibitor (GDI) alpha
Other gene symbolsGDIA1 NPHS8 RHOGDI RHOGDI-1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001772Immunological synapseIEAcellular_component
GO:0005094Rho GDP-dissociation inhibitor activityIEAmolecular_function
GO:0005096GTPase activator activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005856CytoskeletonTAScellular_component
GO:0006928Cellular component movementTASbiological_process
GO:0007162Negative regulation of cell adhesionTASbiological_process
GO:0007264Small GTPase mediated signal transductionTASbiological_process
GO:0007266Rho protein signal transductionIEAbiological_process
GO:0032880Regulation of protein localizationIEAbiological_process
GO:0043066Negative regulation of apoptotic processTASbiological_process
GO:0048011Neurotrophin TRK receptor signaling pathwayTASbiological_process
GO:0050770Regulation of axonogenesisTASbiological_process
GO:0050771Negative regulation of axonogenesisTASbiological_process
GO:0050772Positive regulation of axonogenesisTASbiological_process
GO:0050790Regulation of catalytic activityTASbiological_process
GO:0051056Regulation of small GTPase mediated signal transductionTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.03632454310.18118742830.43281951110.8249822003

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2536600768
GSE13712_SHEARUp1.0998942697
GSE13712_STATICUp0.6356627448
GSE19018Up0.3199925016
GSE19899_A1Down-0.6242689239
GSE19899_A2Up0.2305943489
PubMed_21979375_A1Down-0.0142472968
PubMed_21979375_A2Up0.6003522880
GSE35957Up0.6066500574
GSE36640Down-0.5708516258
GSE54402Up0.3099674652
GSE9593Up0.3636319359
GSE43922Down-0.2143906595
GSE24585Down-0.0006484092
GSE37065Down-0.4191980973
GSE28863_A1Down-0.2765743174
GSE28863_A2Down-0.3470850955
GSE28863_A3Up0.7690388956
GSE28863_A4Up0.0857613219
GSE48662Up0.1963569008

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-16-5pMIMAT0000069MIRT001479pSILAC//Proteomics;OtherFunctional MTI (Weak)18668040
hsa-miR-151a-5pMIMAT0004697MIRT004486qRT-PCR//Luciferase reporter assay//Western blotFunctional MTI20305651
hsa-miR-877-3pMIMAT0004950MIRT036932CLASHFunctional MTI (Weak)23622248
hsa-miR-744-5pMIMAT0004945MIRT037531CLASHFunctional MTI (Weak)23622248
hsa-miR-423-5pMIMAT0004748MIRT038106CLASHFunctional MTI (Weak)23622248
hsa-miR-484MIMAT0002174MIRT042136CLASHFunctional MTI (Weak)23622248
hsa-miR-183-5pMIMAT0000261MIRT047092CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049570CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.