HCSGD entry for LGALS3BP


1. General information

Official gene symbolLGALS3BP
Entrez ID3959
Gene full namelectin, galactoside-binding, soluble, 3 binding protein
Other gene symbols90K BTBD17B MAC-2-BP TANGO10B
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005044Scavenger receptor activityIEAmolecular_function
GO:0005578Proteinaceous extracellular matrixIEAcellular_component
GO:0005615Extracellular spaceTAScellular_component
GO:0006898Receptor-mediated endocytosisTASbiological_process
GO:0006968Cellular defense responseTASbiological_process
GO:0007155Cell adhesionIEAbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0016020MembraneIEAcellular_component
GO:0031012Extracellular matrixIDAcellular_component
GO:0070062Extracellular vesicular exosomeIDAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00457196160.27835836780.17827940741.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1255175043
GSE13712_SHEARUp3.5273789447
GSE13712_STATICUp3.8898023767
GSE19018Down-0.1542233624
GSE19899_A1Down-0.9034630142
GSE19899_A2Down-0.3258146186
PubMed_21979375_A1Down-0.1894167021
PubMed_21979375_A2Up0.3402240075
GSE35957Down-1.2253377485
GSE36640Up1.6514099386
GSE54402Down-0.5988663313
GSE9593Up0.5588209517
GSE43922Down-0.7187605478
GSE24585Up0.2901073582
GSE37065Down-0.0092024621
GSE28863_A1Up0.1514325049
GSE28863_A2Up0.3800910572
GSE28863_A3Up0.4456381030
GSE28863_A4Up0.0674118333
GSE48662Up1.0721838972

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-596MIMAT0003264MIRT007309Luciferase reporter assay//Western blotFunctional MTI23233740
hsa-miR-1MIMAT0000416MIRT024048Proteomics;MicroarrayFunctional MTI (Weak)18668037
hsa-miR-7-5pMIMAT0000252MIRT025918MicroarrayFunctional MTI (Weak)19073608
hsa-miR-296-3pMIMAT0004679MIRT038443CLASHFunctional MTI (Weak)23622248
hsa-miR-26b-3pMIMAT0004500MIRT038953CLASHFunctional MTI (Weak)23622248
hsa-miR-671-5pMIMAT0003880MIRT039290CLASHFunctional MTI (Weak)23622248
hsa-miR-222-3pMIMAT0000279MIRT046598CLASHFunctional MTI (Weak)23622248
hsa-miR-1260bMIMAT0015041MIRT052728CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.