HCSGD entry for LCP1
1. General information
| Official gene symbol | LCP1 |
|---|---|
| Entrez ID | 3936 |
| Gene full name | lymphocyte cytosolic protein 1 (L-plastin) |
| Other gene symbols | CP64 L-PLASTIN LC64P LPL PLS2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001726 | Ruffle | IEA | cellular_component |
| GO:0001891 | Phagocytic cup | IEA | cellular_component |
| GO:0002286 | T cell activation involved in immune response | IDA | biological_process |
| GO:0003779 | Actin binding | IEA NAS | molecular_function |
| GO:0005509 | Calcium ion binding | IEA NAS | molecular_function |
| GO:0005737 | Cytoplasm | IDA NAS | cellular_component |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0005884 | Actin filament | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0015629 | Actin cytoskeleton | IDA | cellular_component |
| GO:0030054 | Cell junction | IEA | cellular_component |
| GO:0031100 | Organ regeneration | IEA | biological_process |
| GO:0032587 | Ruffle membrane | IEA | cellular_component |
| GO:0033157 | Regulation of intracellular protein transport | IDA | biological_process |
| GO:0042802 | Identical protein binding | IEA | molecular_function |
| GO:0051015 | Actin filament binding | IEA | molecular_function |
| GO:0051017 | Actin filament bundle assembly | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1719182326 | 0.3232203906 | 0.8141753013 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1653938479 |
| GSE13712_SHEAR | Up | 0.1471743479 |
| GSE13712_STATIC | Down | -0.0917773030 |
| GSE19018 | Up | 0.0940478332 |
| GSE19899_A1 | Up | 0.1546530309 |
| GSE19899_A2 | Up | 0.1013100625 |
| PubMed_21979375_A1 | Up | 0.5114583090 |
| PubMed_21979375_A2 | Up | 0.0180365219 |
| GSE35957 | Down | -0.0790612234 |
| GSE36640 | Down | -0.0927451217 |
| GSE54402 | Up | 0.5599146363 |
| GSE9593 | Up | 0.1547758634 |
| GSE43922 | Up | 1.4492416791 |
| GSE24585 | Down | -0.2192050732 |
| GSE37065 | Down | -0.0509597288 |
| GSE28863_A1 | Down | -0.8818160305 |
| GSE28863_A2 | Down | -1.0070829094 |
| GSE28863_A3 | Up | 0.0674285256 |
| GSE28863_A4 | Up | 0.0955498796 |
| GSE48662 | Up | 0.0245307138 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023871 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-520a-3p | MIMAT0002834 | MIRT041160 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
