HCSGD entry for LCN1

1. General information

Official gene symbolLCN1
Entrez ID3933
Gene full namelipocalin 1
Other gene symbolsPMFA TLC TP VEGP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004869Cysteine-type endopeptidase inhibitor activityTASmolecular_function
GO:0005576Extracellular regionIEAcellular_component
GO:0006508ProteolysisTASbiological_process
GO:0006810TransportIEAbiological_process
GO:0010466Negative regulation of peptidase activityTASbiological_process
GO:0010951Negative regulation of endopeptidase activityTASbiological_process
GO:0043086Negative regulation of catalytic activityTASbiological_process
GO:0050790Regulation of catalytic activityTASbiological_process
GO:0050896Response to stimulusIEAbiological_process
GO:0050909Sensory perception of tasteIEAbiological_process
GO:0052547Regulation of peptidase activityTASbiological_process
GO:0052548Regulation of endopeptidase activityTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.70251722580.41916058660.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2314578358
GSE13712_SHEARUp0.0699054432
GSE13712_STATICUp0.0819005222
GSE19018Up0.2785174861
GSE19899_A1Down-0.1383930025
GSE19899_A2Up0.2645360752
PubMed_21979375_A1Up0.0515027812
PubMed_21979375_A2Down-0.2162312987
GSE35957Down-0.1059643814
GSE36640Up0.0653068788
GSE54402Up0.0004614243
GSE9593Up0.0645400844
GSE43922Up0.1609967045
GSE24585Up0.0351165500
GSE37065Down-0.2196192964
GSE28863_A1Down-0.1888715026
GSE28863_A2Down-0.2928467204
GSE28863_A3Up0.1678505077
GSE28863_A4Down-0.0098072499
GSE48662Up0.2006425830

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018097MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.