HCSGD entry for LAMB3
1. General information
| Official gene symbol | LAMB3 |
|---|---|
| Entrez ID | 3914 |
| Gene full name | laminin, beta 3 |
| Other gene symbols | BM600-125KDA LAM5 LAMNB1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005198 | Structural molecule activity | NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005610 | Laminin-5 complex | IEA | cellular_component |
| GO:0007155 | Cell adhesion | IEA | biological_process |
| GO:0008544 | Epidermis development | TAS | biological_process |
| GO:0030198 | Extracellular matrix organization | TAS | biological_process |
| GO:0031581 | Hemidesmosome assembly | TAS | biological_process |
| GO:0032403 | Protein complex binding | IEA | molecular_function |
| GO:0034329 | Cell junction assembly | TAS | biological_process |
| GO:0050873 | Brown fat cell differentiation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0018643023 | 0.9739618783 | 0.1149590164 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4361795819 |
| GSE13712_SHEAR | Up | 0.5021483621 |
| GSE13712_STATIC | Up | 1.9050710278 |
| GSE19018 | Up | 0.1576568847 |
| GSE19899_A1 | Up | 0.1291691330 |
| GSE19899_A2 | Up | 0.7223851216 |
| PubMed_21979375_A1 | Up | 1.5608286524 |
| PubMed_21979375_A2 | Up | 0.6007181203 |
| GSE35957 | Down | -0.0607040737 |
| GSE36640 | Down | -1.0143757160 |
| GSE54402 | Up | 1.3606646367 |
| GSE9593 | Up | 0.6232500255 |
| GSE43922 | Up | 0.6513034924 |
| GSE24585 | Down | -0.2617441452 |
| GSE37065 | Up | 0.5016519416 |
| GSE28863_A1 | Up | 0.0424195112 |
| GSE28863_A2 | Up | 0.5977367434 |
| GSE28863_A3 | Up | 0.1495451786 |
| GSE28863_A4 | Up | 0.0135512422 |
| GSE48662 | Up | 0.6881420352 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-218-5p | MIMAT0000275 | MIRT001062 | qRT-PCR//Western blot//Northern blot//Luciferase reporter assay | Functional MTI | 17998940 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT023092 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031939 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-218-5p | MIMAT0000275 | NA | hsa-miR-218 | 17998940 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
