HCSGD entry for LAMB2
1. General information
| Official gene symbol | LAMB2 |
|---|---|
| Entrez ID | 3913 |
| Gene full name | laminin, beta 2 (laminin S) |
| Other gene symbols | LAMS NPHS5 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005178 | Integrin binding | IEA | molecular_function |
| GO:0005198 | Structural molecule activity | NAS | molecular_function |
| GO:0005604 | Basement membrane | IDA | cellular_component |
| GO:0005605 | Basal lamina | TAS | cellular_component |
| GO:0005608 | Laminin-3 complex | IEA IPI | cellular_component |
| GO:0007155 | Cell adhesion | IEA | biological_process |
| GO:0007411 | Axon guidance | IEA | biological_process |
| GO:0007528 | Neuromuscular junction development | IEA | biological_process |
| GO:0007601 | Visual perception | IEA | biological_process |
| GO:0014002 | Astrocyte development | IEA | biological_process |
| GO:0014044 | Schwann cell development | IEA | biological_process |
| GO:0030198 | Extracellular matrix organization | TAS | biological_process |
| GO:0031012 | Extracellular matrix | IDA ISS | cellular_component |
| GO:0043260 | Laminin-11 complex | TAS | cellular_component |
| GO:0045202 | Synapse | IEA | cellular_component |
| GO:0048677 | Axon extension involved in regeneration | IEA | biological_process |
| GO:0060041 | Retina development in camera-type eye | IEA | biological_process |
| GO:0072249 | Metanephric glomerular visceral epithelial cell development | IEA | biological_process |
| GO:0072274 | Metanephric glomerular basement membrane development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1018428289 | 0.0067742373 | 0.6642680624 | 0.1645488930 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.5787382403 |
| GSE13712_SHEAR | Down | -0.3118279575 |
| GSE13712_STATIC | Down | -0.1180410938 |
| GSE19018 | Up | 1.0666175420 |
| GSE19899_A1 | Down | -1.0687756959 |
| GSE19899_A2 | Down | -1.4183216472 |
| PubMed_21979375_A1 | Down | -1.9999313241 |
| PubMed_21979375_A2 | Down | -0.0109912640 |
| GSE35957 | Down | -0.8337369759 |
| GSE36640 | Up | 0.6903685119 |
| GSE54402 | Down | -0.8947357584 |
| GSE9593 | Up | 0.1315300754 |
| GSE43922 | Down | -0.5804854642 |
| GSE24585 | Up | 0.7625201045 |
| GSE37065 | Down | -0.4650374132 |
| GSE28863_A1 | Up | 0.9457809784 |
| GSE28863_A2 | Up | 0.5572374237 |
| GSE28863_A3 | Down | -0.1633702497 |
| GSE28863_A4 | Down | -0.3210466753 |
| GSE48662 | Up | 0.5442924878 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-484 | MIMAT0002174 | MIRT042388 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-196b-5p | MIMAT0001080 | MIRT042683 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
