HCSGD entry for RND3
1. General information
| Official gene symbol | RND3 |
|---|---|
| Entrez ID | 390 |
| Gene full name | Rho family GTPase 3 |
| Other gene symbols | ARHE Rho8 RhoE memB |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | IEA | cellular_component |
| GO:0003924 | GTPase activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0006184 | GTP catabolic process | TAS | biological_process |
| GO:0007155 | Cell adhesion | TAS | biological_process |
| GO:0007264 | Small GTPase mediated signal transduction | IEA | biological_process |
| GO:0008152 | Metabolic process | TAS | biological_process |
| GO:0030036 | Actin cytoskeleton organization | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0474994719 | 0.2958346795 | 0.4817750385 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5919512930 |
| GSE13712_SHEAR | Up | 0.4215859402 |
| GSE13712_STATIC | Up | 0.7057047155 |
| GSE19018 | Down | -0.3043675799 |
| GSE19899_A1 | Down | -0.0507633659 |
| GSE19899_A2 | Down | -0.0768541782 |
| PubMed_21979375_A1 | Up | 0.2065599474 |
| PubMed_21979375_A2 | Up | 0.3733701563 |
| GSE35957 | Up | 0.1751727365 |
| GSE36640 | Up | 0.6689569461 |
| GSE54402 | Down | -0.0440043923 |
| GSE9593 | Up | 1.2560566027 |
| GSE43922 | Up | 0.0478666809 |
| GSE24585 | Down | -0.6598017331 |
| GSE37065 | Up | 0.8008744788 |
| GSE28863_A1 | Down | -0.6525466132 |
| GSE28863_A2 | Up | 0.6875059202 |
| GSE28863_A3 | Down | -0.3033900619 |
| GSE28863_A4 | Down | -0.1367742029 |
| GSE48662 | Down | -0.4379554629 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Guanosine-5'-Triphosphate | DB04137 | EXPT01660 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-200b-3p | MIMAT0000318 | MIRT006511 | Luciferase reporter assay | Functional MTI | 20683643 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT006689 | Luciferase reporter assay//qRT-PCR//Western blot | Functional MTI | 22132820 |
| hsa-miR-421 | MIMAT0003339 | MIRT016130 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027467 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT027956 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028467 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
