HCSGD entry for L1CAM

1. General information

Official gene symbolL1CAM
Entrez ID3897
Gene full nameL1 cell adhesion molecule
Other gene symbolsCAML1 CD171 HSAS HSAS1 MASA MIC5 N-CAM-L1 N-CAML1 NCAM-L1 S10 SPG1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005178Integrin bindingIEAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0006935ChemotaxisTASbiological_process
GO:0007155Cell adhesionNASbiological_process
GO:0007156Homophilic cell adhesionIEAbiological_process
GO:0007157Heterophilic cell-cell adhesionIEAbiological_process
GO:0007159Leukocyte cell-cell adhesionIEAbiological_process
GO:0007166Cell surface receptor signaling pathwayIEAbiological_process
GO:0007399Nervous system developmentTASbiological_process
GO:0007411Axon guidanceIEA TASbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0008219Cell deathIEAbiological_process
GO:0009897External side of plasma membraneIEAcellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0022409Positive regulation of cell-cell adhesionIEAbiological_process
GO:0033631Cell-cell adhesion mediated by integrinIEAbiological_process
GO:0033691Sialic acid bindingIEAmolecular_function
GO:0034109Homotypic cell-cell adhesionIEAbiological_process
GO:0042734Presynaptic membraneIEAcellular_component
GO:0042802Identical protein bindingIEAmolecular_function
GO:0043195Terminal boutonIEAcellular_component
GO:0043621Protein self-associationIEAmolecular_function
GO:0050850Positive regulation of calcium-mediated signalingIEAbiological_process
GO:0050900Leukocyte migrationTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00018969260.99677004290.03994320001.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1434960674
GSE13712_SHEARUp0.0102896154
GSE13712_STATICUp0.1028118207
GSE19018Up0.5134391666
GSE19899_A1Up1.4567699231
GSE19899_A2Up2.5554838227
PubMed_21979375_A1Up2.3821205131
PubMed_21979375_A2Up3.0630254236
GSE35957Down-0.0118983002
GSE36640Up2.2406237011
GSE54402Up0.4127029482
GSE9593Up0.0303949912
GSE43922Up1.5483978218
GSE24585Down-0.2174565556
GSE37065Up0.0448074311
GSE28863_A1Down-0.0790379315
GSE28863_A2Up1.7824308823
GSE28863_A3Up0.8959358186
GSE28863_A4Up0.1192512288
GSE48662Up0.0607419649

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT019015MicroarrayFunctional MTI (Weak)18185580
hsa-miR-124-3pMIMAT0000422MIRT023076MicroarrayFunctional MTI (Weak)18668037
hsa-miR-1MIMAT0000416MIRT024085ProteomicsFunctional MTI (Weak)18668040
hsa-miR-26b-5pMIMAT0000083MIRT030212MicroarrayFunctional MTI (Weak)19088304
hsa-miR-16-5pMIMAT0000069MIRT032036ProteomicsFunctional MTI (Weak)18668040
hsa-miR-146a-5pMIMAT0000449MIRT035533Luciferase reporter assayFunctional MTI22711166
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.