HCSGD entry for IYD
1. General information
| Official gene symbol | IYD |
|---|---|
| Entrez ID | 389434 |
| Gene full name | iodotyrosine deiodinase |
| Other gene symbols | C6orf71 DEHAL1 TDH4 dJ422F24.1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004447 | Iodide peroxidase activity | IEA | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006590 | Thyroid hormone generation | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016491 | Oxidoreductase activity | IEA TAS | molecular_function |
| GO:0034641 | Cellular nitrogen compound metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3868300027 | 0.9294679533 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2410264190 |
| GSE13712_SHEAR | Up | 0.1516737374 |
| GSE13712_STATIC | Down | -0.0587874115 |
| GSE19018 | Down | -0.0230541897 |
| GSE19899_A1 | Up | 0.0036166427 |
| GSE19899_A2 | Up | 0.0950826719 |
| PubMed_21979375_A1 | Down | -0.0552284597 |
| PubMed_21979375_A2 | Down | -0.2387462522 |
| GSE35957 | Up | 0.2863907345 |
| GSE36640 | Up | 0.1707050807 |
| GSE54402 | Down | -0.0333683333 |
| GSE9593 | Up | 0.2664317478 |
| GSE43922 | Up | 0.0348950343 |
| GSE24585 | Up | 0.0934587280 |
| GSE37065 | Up | 0.0525893475 |
| GSE28863_A1 | Up | 0.0546334267 |
| GSE28863_A2 | Up | 0.2297604399 |
| GSE28863_A3 | Up | 0.2134858109 |
| GSE28863_A4 | Down | -0.0453752625 |
| GSE48662 | Down | -0.0193783796 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| 3,5-Diiodotyrosine | DB03374 | EXPT03137 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017241 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
