HCSGD entry for KRT4
1. General information
| Official gene symbol | KRT4 |
|---|---|
| Entrez ID | 3851 |
| Gene full name | keratin 4 |
| Other gene symbols | CK-4 CK4 CYK4 K4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005198 | Structural molecule activity | IEA | molecular_function |
| GO:0005882 | Intermediate filament | NAS | cellular_component |
| GO:0007010 | Cytoskeleton organization | NAS | biological_process |
| GO:0030855 | Epithelial cell differentiation | ISS | biological_process |
| GO:0045095 | Keratin filament | IEA | cellular_component |
| GO:0050680 | Negative regulation of epithelial cell proliferation | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4616301926 | 0.9126005395 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1238823827 |
| GSE13712_SHEAR | Up | 0.0478326853 |
| GSE13712_STATIC | Up | 0.0160282029 |
| GSE19018 | Up | 0.0576257736 |
| GSE19899_A1 | Up | 0.0978853219 |
| GSE19899_A2 | Up | 0.0935138856 |
| PubMed_21979375_A1 | Up | 0.0546942314 |
| PubMed_21979375_A2 | Up | 0.2201933216 |
| GSE35957 | Up | 0.1598368106 |
| GSE36640 | Up | 0.0991747332 |
| GSE54402 | Up | 0.0346046762 |
| GSE9593 | Up | 0.0764426778 |
| GSE43922 | Up | 0.0258595556 |
| GSE24585 | Down | -0.0449420270 |
| GSE37065 | Up | 0.1080044030 |
| GSE28863_A1 | Down | -0.2829552219 |
| GSE28863_A2 | Down | -0.0821149979 |
| GSE28863_A3 | Up | 0.2360224379 |
| GSE28863_A4 | Up | 0.2949806529 |
| GSE48662 | Up | 0.0749374176 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017456 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029264 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
