HCSGD entry for IPO5
1. General information
Official gene symbol | IPO5 |
---|---|
Entrez ID | 3843 |
Gene full name | importin 5 |
Other gene symbols | IMB3 KPNB3 Pse1 RANBP5 imp5 |
Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network

This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
---|---|---|---|
GO:0005095 | GTPase inhibitor activity | TAS | molecular_function |
GO:0005515 | Protein binding | IPI | molecular_function |
GO:0005634 | Nucleus | IEA ISS | cellular_component |
GO:0005643 | Nuclear pore | TAS | cellular_component |
GO:0005730 | Nucleolus | IEA | cellular_component |
GO:0005737 | Cytoplasm | ISS | cellular_component |
GO:0006607 | NLS-bearing protein import into nucleus | IEA ISS | biological_process |
GO:0006610 | Ribosomal protein import into nucleus | IDA | biological_process |
GO:0006886 | Intracellular protein transport | IEA | biological_process |
GO:0008536 | Ran GTPase binding | IEA | molecular_function |
GO:0008565 | Protein transporter activity | IEA ISS | molecular_function |
GO:0016032 | Viral process | IEA | biological_process |
GO:0042307 | Positive regulation of protein import into nucleus | ISS | biological_process |
GO:0043086 | Negative regulation of catalytic activity | TAS | biological_process |
GO:0050790 | Regulation of catalytic activity | TAS | biological_process |
GO:0071230 | Cellular response to amino acid stimulus | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
p-value up | p-value down | FDR up | FDR down |
---|---|---|---|
0.1802478477 | 0.2080101212 | 0.8321879670 | 0.8832194973 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
Data source | Up or down | Log fold change |
---|---|---|
GSE11954 | Down | -0.1573931866 |
GSE13712_SHEAR | Down | -0.2769562290 |
GSE13712_STATIC | Down | -0.1832223316 |
GSE19018 | Up | 0.0091967966 |
GSE19899_A1 | Down | -0.2634164380 |
GSE19899_A2 | Down | -0.1320431006 |
PubMed_21979375_A1 | Up | 0.3787699307 |
PubMed_21979375_A2 | Down | -0.0518132257 |
GSE35957 | Up | 0.2798142975 |
GSE36640 | Down | -0.6423127058 |
GSE54402 | Up | 0.2095651700 |
GSE9593 | Down | -0.0108914126 |
GSE43922 | Down | -0.0102816076 |
GSE24585 | Down | -0.3813247307 |
GSE37065 | Down | -0.3869783547 |
GSE28863_A1 | Up | 1.2735107125 |
GSE28863_A2 | Up | 0.8683195049 |
GSE28863_A3 | Up | 0.5946964254 |
GSE28863_A4 | Up | 0.0102298947 |
GSE48662 | Down | -0.3170255232 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
---|---|---|---|---|---|
hsa-miR-1296-5p | MIMAT0005794 | MIRT036092 | CLASH | Functional MTI (Weak) | 23622248 |
hsa-miR-877-3p | MIMAT0004950 | MIRT036844 | CLASH | Functional MTI (Weak) | 23622248 |
hsa-miR-484 | MIMAT0002174 | MIRT041786 | CLASH | Functional MTI (Weak) | 23622248 |
hsa-miR-324-5p | MIMAT0000761 | MIRT043188 | CLASH | Functional MTI (Weak) | 23622248 |
hsa-miR-222-3p | MIMAT0000279 | MIRT046603 | CLASH | Functional MTI (Weak) | 23622248 |
hsa-miR-196a-5p | MIMAT0000226 | MIRT048251 | CLASH | Functional MTI (Weak) | 23622248 |
hsa-miR-93-5p | MIMAT0000093 | MIRT048827 | CLASH | Functional MTI (Weak) | 23622248 |
hsa-miR-92a-3p | MIMAT0000092 | MIRT049490 | CLASH | Functional MTI (Weak) | 23622248 |
hsa-miR-16-5p | MIMAT0000069 | MIRT051154 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
---|---|
15034937 | Using bioinformatics-, Western-blotting-, yeast-two-hybrid-system-, polymerase chain reaction (PCR)-, and fluorescence microscopy-analyses, we demonstrate here that the neuroprotective protein p60TRP (p60-transcription-regulator-protein) is a basic helix-loop-helix (bHLH) domain-containing member of a new protein family that interacts with the Ran-binding-protein-5 (RanBP5) and the protein-phosphatase-2A (PP2A) |
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