HCSGD entry for KLRD1
1. General information
| Official gene symbol | KLRD1 |
|---|---|
| Entrez ID | 3824 |
| Gene full name | killer cell lectin-like receptor subfamily D, member 1 |
| Other gene symbols | CD94 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004888 | Transmembrane signaling receptor activity | TAS | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0007166 | Cell surface receptor signaling pathway | TAS | biological_process |
| GO:0009897 | External side of plasma membrane | IEA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030246 | Carbohydrate binding | IEA | molecular_function |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0050776 | Regulation of immune response | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6914538733 | 0.6806809506 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0027084705 |
| GSE13712_SHEAR | Down | -0.0559854914 |
| GSE13712_STATIC | Up | 0.0650553832 |
| GSE19018 | Up | 0.0081562266 |
| GSE19899_A1 | Down | -0.0500334213 |
| GSE19899_A2 | Up | 0.1124376586 |
| PubMed_21979375_A1 | Down | -0.0302817193 |
| PubMed_21979375_A2 | Up | 0.1184469456 |
| GSE35957 | Up | 0.0388697308 |
| GSE36640 | Up | 0.4029395049 |
| GSE54402 | Up | 0.0212290243 |
| GSE9593 | Down | -0.0018817878 |
| GSE43922 | Up | 0.0185624490 |
| GSE24585 | Up | 0.1139612348 |
| GSE37065 | Up | 0.1501564552 |
| GSE28863_A1 | Up | 0.0468714352 |
| GSE28863_A2 | Down | -0.3515993019 |
| GSE28863_A3 | Up | 0.0839596337 |
| GSE28863_A4 | Down | -0.2781399908 |
| GSE48662 | Up | 0.0538494338 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 19220836 | Natural killer (NK)-like T cell receptors (CD94, 158) and intracellular perforin, granzyme B were increased in CD4(+)CD28(null) cells |
| 19220836 | These CD4(+)CD28(null) T cells show increased expression of NK-like T cell receptors (CD94, 158) and intracellular perforin and granzyme B |
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